The article contains a comprehensive analysis of the evolution of science & technology history studies on the territory of Ukraine. Its first stage covered the late XIX - early XX century, when irregular studies on S&T history were conducted in universities. The second stage began with establishing the Ukrainian Academy of Sciences (UAS) in 1918, and continued till 1928. The third stage was marked by conceptualization of S&T history studies in 1928, and organization of a specialized commission at the UAS on studies of the development of scientific thought in Ukraine, which, however, was not realized due to mass-scale repressions starting in 1929. The third stage, marked by expanding and systematizing of studies on S&T history, began in the post-war period, with opening the first vacancy on science history in Academy in 1948, and organizing the Ukrainian Affiliation of the National Union of S&T Historians in 1958. The fourth stage began with organizing the Unit of S&T History within the Institute for History of the Academy of Sciences of the Ukrainian SSR in 1963, and launching studies on science of science within the Cybernetics Institute under the supervision of G.M.Dobrov. Contributions to S&T history studies made by various research institutions, public associations and individual scientists at every evolution stage are shown in great detail.