In this paper, we present the territorial partnership issue and its influence on regional and local development. Partnerships are territorial unions of subjects from the public, non-government and the private sector. By this kind of cooperation, it is possible to use the level of social activity to mobilize local and regional resources for economic and social development. It was necessary to present a few crucial concepts of partnership. Attention has also been drawn from regional and local politics and the increase of a region's role in the global economy. To show how important the territorial partnership's influence is on a region and its social development, selected examples have been presented.