The article deals with the research of a short interval, when the Ministry of Health Care tried realising an idea to establish independent pharmaceutical industry focused at the biological products. The idea of the Ministry to retain own industry was not traditional not only in relation to its own history but also to the deep-rooted character of ministries' of health care competence. Nationalised pharmaceutical industry belonged to the Ministry of Industry as regards competence. Nevertheless, it was one of the most profitable branches of the Czechoslovak industry in the given period. Therefore the Ministry of Health Care got into question of jurisdiction with the Ministry of Industry, and it prepared a project of an enterprise with the operative name Biotika that was to arch over the pharmaceutical production. The Ministry of Health Care was successful finally after many negotiations, and it established its own pharmaceutical national enterprise of the resulting name Biogena with the effect from January 1, 1950.