The author deals with the importance of memories in connection with historical buildings and sites. The theoretical framework of the study is the concept of space and place (mostly in approach of S. Low) and collective memory (M. Halbwachs). Abstract space is transformed through human activities, interpersonal relationships, communication, memories, etc. into a known place with sense and specific meanings for certain people. Collective memory (the social representation of the past) plays an important role in this process of change. On the other hand, the memories are bound to a certain place, that is to say they are spatially anchored. In this study, the author observes what memories are related to the buildings and the site of the old hospital in Topoľčany. His informants were its former employees, doctors and nurses and the main method used was ethnographic semi-structured interview.