For centuries the issue of Filioque, that is, whether the Holy Spirit proceeds not only from the Father, but also from the Son, has been debated. It gives rise to a further question, namely, whether the Spirit of God can also proceed from a human being. Some biblical texts, as well as statements of mystics, suggest a positive answer, yet assuming it may seem presumptuous. The author of this paper searches for an answer to this question. First she presents the main arguments used by Filioque advocates to defend their faith and then she reflects on their testimonial value with respect to the first and second questions. Subsequently she pays attention to two relevant texts from the Gospel of John. Based on theological arguments implied by the analogy of faith and the analogy of being and also based on what Scripture says the author reaches the conclusion that spiration of the Spirit of God by human beings is grounded and that the human vocation is realized in it. From orthodoxy she draws implications for orthopraxis.