Backcground. Depression is one of the most severe health issues of the modern medicine. The aim of this study was to evaluate the relationship between depression and neck pain. Material and method. The study involved 60 patients aged 37–82 years (mean age: 63 ± 10 years) treated for neck pain at the Rehabilitation Department of Zamość University of Management and Administration. Depression symptoms were assessed with a Zung Self-Rating Depression Scale (SDS). It was also used a Acceptance of Illness Scale. Results. The studied group demonstrated statistically significant decrease of depression after rehabilitation (SDS: p<0,001). The research did not show statistically significant increase of acceptance of illness degree (AIS: p=0,48). Conclusions. Rehabilitation decreases intensity of depression. In a subjective opinion, rehabilitation has no improvement on acceptance of illness degree.