The article is devoted to the analysis of tolerance and xenophobia of the Ukrainians of the Trans-Carpathian region towards some ethnic groups. Based on the opinion polls conducted according to Bogardus method of measuring of social distance, the author analysed the attitude to the Russian speaking Ukrainians, the Hungarians, the Romanians, the Russians, the Roma, the Slovaks, the Jews, the Americans and the Hindus. The survey results indicate that the Ukrainians of the Trans-Carpathian region mostly demonstrate their tolerance towards the Slovaks, the Americans and the Russian-speaking Ukrainians. The social distance to the Hungarians, the Romanians, the Jews and the Hindus can be characterised as alienation. There is an openly xenophobic attitude towards the Russians and the Roma people.