Effects of the climate change appear in several fields of the economy and agriculture can be considered as one of the most affected among them. In a country, where almost 10% of the total GDP is produced by the agricultural sector and more than 30% of the total work force is employed in this field, these changes may have severe economic impacts. As in Romania almost 65% of the agricultural production is represented by vegetal production, we concentrate our investigations on this agricultural sector. Our aim is to present, basing on econometric modeling, how the climate changes will affect the Romanian crop production in the next 20 years, highlighting the territorial differences which appear between the Romanian NUTS2 development regions. This paper presents some of the first results of the FP6 research project “CLAVIER – Climate Change and Variability: Impact on Central and Eastern Europe”, contract no. 037013 (2006-2009).