The framework of Technological Pedagogical Content Knowledge (TPCK) has been developed as a valuable tool for understanding the ways for effective technology use in the teaching process. Due to continuous innovations in education technologies, educators experience some difficulties how to implement the appropriate technology and correlate it with learning goals, students’ needs, content of the subjects and pedagogical strategy. It caused the separation of the educational technology and situational educational process. TPCK framework can bridge the gap and promotes how to combine classical pedagogical strategies and contemporary technologies. This study focuses on the description and analysis of practical TPCK framework implementation at English Language classes for bachelors at technical university. The paper suggest examples of redesigned learning activities according to TPCK framework concepts in order to enhance students’ language skills. The results of the practical implementation observations and students’ as well as teachers’ reflective blogs demonstrated the benefits and challenges of the approach. Students’ feedback evidenced the meaningful impact on their academic achievements and improvement of language competence. Moreover, the described tool can be used as an indicator to assess teachers’ knowledge of content, pedagogy and level of digital competence in terms of the professional development.