The article is concerned with the role of madness in the works of Nietzsche. The German philosopher saw many conceptions and human activities as manifestation of madness. These include: happiness, wisdom, truth, faith in god(s), purity, morality, debauchery, virtues, honesty, live, mercy, compassion, power, wealth, marriage, genius, super humanity, conformism, literary activity, idealism, nobility and some religious-philosophical conception. In the end also reason and will were for him symptoms of madness. According to him culture, art and development of civilization lead people to madness. In fact Nietzsche identifies madness with humanity.