The development of Web 2.0 tools has made it possible to create channels of synchronic and interactive communication. Researchers increasingly work online, create virtual communities in which their share their scholarly publications, use peer reviewing and folksonomy. Scientific circles could benefit alot from ashared infrastructure that would allow them to remotely access information resources and directly use the data available on the Internet. An example of such an effective world network in GEANT, which links over 3000 research centers from over 30 countries. E-Science consists in bringing together tools and services that make it possible to create virtual laboratories. The task of the Grenoble-based MI2S is to inform the IT and applied mathematics community about the various research tasks and needs with regard to e-Science. Since 2010, the entities cooperating in Grenoble include G-Scop, GIPSA-lab, LIG, LJK, MaiMoSiNE, TIMA, TIMC, VERIMAG. The service is used by 400 users and it is linked to 150 projects. French scientists take advantage of possibilities offered by GRID5000, the GEANT network, Renater (Réseau National de télécommunications pour la Technologie l’Enseignement et la Recherche). Currently operating platforms include CIMENT and Dimocode.