EN
Crop protection against plant pathogenic fungi is one of the basics ensuring high yields. Unfortunately, resistance to fungicides has the tendency to occur more frequently. The causes of the decline of active substances protective effect are usually mutations in genes of fungicide target proteins. The other factors of increasing resistance level include overexpression of target protein, synthesis of alternative enzymes replacing functions of inhibited enzymes or removal of fungicides from cells by ABC and MFS protein transporters. Currently, due to the increased incidence of this phenomenon is important to use fungicides according to practices preventing the formation of fungi resistance.