Unfinished first-line tuberculosis treatment in primary care in Indonesia

• Authors: Asyary Al , Mahendradhata Yodi
• Languages of publication: EN

Abstracts

EN

Background. Unfinished tuberculosis (TB) treatment has slowly but surely become an unexpected event in the disease’s development into drug-resistant TB. Developing countries, mostly comprised of Asian and Eastern European countries, including Indonesia, have been overwhelmed in preventing drug-resistant TB outcomes and have also failed to avoid the development of this disease. Objectives. This review discusses the current issue of an unfinished first-line TB treatment strategy in primary care in Indonesia, presenting some relevant strategies in developing countries. Material and methods. A narrative review approach conducted on all existing evidence in selected scientific bibliographic sources. The researchers defined the keywords based on the research question as a search strategy. Results. Scarce resources and limited access, alongside national policy on TB control and management, contribute in different ways to impede first-line TB treatment in Indonesia. Empowerment of TB patients and their families are considered the best ways to increase awareness on TB medication in a low- to middle-income setting. The role of the hospital and private practitioner networks in the treatment and management of TB patients is essential for developing active-case-finding-approach programs for TB suspects in primary care in an Indonesian setting. Contrarily, the potential misunderstandings in TB treatment have led to peculiar events affected by poor surveillance systems for TB investigation contacts to prevent TB incidences in large populations. Conclusions. This study addressed the barrier of all stakeholders, particularly primary care, to achieve the Indonesian government’s goals of TB elimination by 2030 and zero TB findings by 2050

Keywords

EN

tuberculosis; drug resistance; Indonesia; developing countries; primary care.

• Publisher: Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
• Journal: Family Medicine & Primary Care Review
• Year: 2019
• Issue: 2
• Pages: 185-188

Contributors

author

Asyary Al

author

Mahendradhata Yodi

References

• World Health Organization. Global Tuberculosis Control 2011. Geneva: WHO; 2011: 38.
• He GX, Wang HY, Borgdorff MW, et al. Multidrug-resistant tuberculosis, people’s Republic of China, 2007-2009. Emerg Infect Dis 2011;17(10): 1831–1838.
• Porwal C, Kaushik A, Makkar N, et al. Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi Region. PLoS ONE 2013; 8: e5529, doi: https://doi.org/10.1371/journal.pone.0055299.
• Terlikbayeva A, Hermosilla S, Galea S, et al. Tuberculosis in Kazakhstan: an analysis of risk determinants in national surveillance data.BMC Infec Dis 2012; 12: 1–9, doi: 10.1186/1471-2334-12-262.
• Nagaraja SB, Satyanarayana S, Chadha SS, et al. How do patients who fail first-line tb treatment but who are not placed on an MDR-TB Regimen Fare in South India. PLoS ONE 2011; 6(10): e25698, doi: 10.1371/journal.pone.0025698.
• Wells WA, Ge CF, Patel N, et al. Size and usage patterns of private TB Drug Markets in the high burden countries. PLoS ONE 2011; 6(5):e18964, doi: 10.1371/journal.pone.0018964.
• Lin H, Shin S, Blaya JA, et al. Assessing spatiotemporal patterns of multidrug-resistant and drug-sensitive tuberculosis in a South American setting. Epidemiol Infect 2011; 139: 1784–1793.
• Park PH, Magut C, Gardner A, et al. Increasing access to the MDR-TB surveillance programme through a collaborative model in western Kenya. Trop Med Int Health 2012; 17(3): 374–379.
• Brust JCM, Shah SN, Scott M, et al. Integrated, home-based treatment for MDR-TB and HIV in rural South Africa: an alternate model of care. Int J Tuberc Lung Dis 2012; 16: 998–1004.
• Brust JCM, Gandhi NR, Carrara H, et al. High treatment failure and default rates for patients with MDR TB in KwaZulu-Natal, South Africa, 2000–2003. Int J Tuberc Lung Dis 2011; 14: 413–419.
• Tyszko PZ, Nitsch-Osuch A, Mińko M, et al. Primary health care tasks in implementing the main operations of public health. Fam Med Prim Care Rev 2016; 18(3): 394–397.
• Usman MM, Ismail S, Teoh TC. Vaccine research and development: tuberculosis as a global health threat. Cent Eur J Immunol 2017;42(2): 196–204, doi: dx.doi.org/10.5114/ceji.2017.69362.
• TB Indonesia. Multi-drug Resistant TB [Internet]. Directorate General for Disease Control and Environment Health, Indonesian Ministry of Health 2012 [cited 9.02.2015]. Available from URL: http://www.tbindonesia.or.id/tb-mdr/.
• Ditjen-P2PL. Strategi Nasional Pengendalian TB Di Indonesia 2010–2014. Stop TB: Terobosan Menuju Akses Universal. Jakarta: Direktorat Jenderal Pengendalian Penyakit dan Penyehatan Lingkungan; 2011: 80.
• Mahendradhata Y, Utarini A, Lazuardi U, et al. Private practitioners and tuberculosis case detection in Jogjakarta, Indonesia: actual role and potential. Trop Med Int Health 2007; 12(10): 1218–1224.
• Probandari A, Lindholm L, Stenlund H, et al. Missed opportunity for standardized diagnosis and treatment among adult Tuberculosis patients in hospitals involved in public-private mix for directly observed treatment short-course strategy in Indonesia: a cross-sectional study. BMC Health Serv Res 2010; 10(113): 113, doi: 10.1186/1472-6963-10-113.
• Ditjen-P2PL. Programmatic Management of Drug Resistance Tuberculosis Pengendalian Tuberkulosis. Rencana Aksi Nasional Indonesia 2010–2014. Jakarta, Indonesia: Kementerian Kesehatan Direktorat Jenderal Pengendalian Penyakit dan Penyehatan Lingkungan; 2011.
• Utarini A, Probandari A, Lestari T, et al. Assessment of hospital DOTS implementation: component A. TB and HIV caseload in hospitals and clinics. Yogyakarta: Hospital Management Program, Postgraduate Program of Public Health, Faculty of Medicine – Universitas Gadjah Mada; 2007.
• Utarini A, Probandari A, Lestari T, et al. Assessment of hospital DOTS implementation: component B. Implementation of DOTS hospital,TB-HIV collaboration and MDR-TB management. Yogyakarta: Hospital Management Program, Postgraduate Program of Public Health,Faculty of Medicine – Universitas Gadjah Mada; 2008.
• Probandari A, Utarini A, Lindholm L, et al. Life of a partnership: the process of collaboration between the National Tuberculosis Program and the hospitals in Yogyakarta, Indonesia. Soc Sci Med 2011; 73(9): 1386–1394.
• Paramasivan CN, Lee E, Kao K, et al. Experience establishing tuberculosis laboratory capacity in a developing country setting. Int J Tuberc Lung Dis 2010; 14: 59–64.
• P2PL D. Rencana Aksi Nasional Programmatic management of drug resistance tuberculosis pengendalian tuberkulosis Indonesia:2011–2014. Jakarta: Kementerian Kesehatan RI; 2011: 66.
• Mkopi A, Range N, Amuri M, et al. Health workers ’ performance in the implementation of Patient Centred Tuberculosis Treatment (PCT)strategy under programmatic conditions in Tanzania: a cross sectional study. BMC Health Serv Res 2013; 13: 101, doi: 10.1186/1472-6963-13-101.
• Egwaga S, Range N, Lwilla F, et al. Assessment of patient preference in allocation and observation of anti-tuberculosis medication in three districts in Tanzania. Patient Prefer Adherence 2008; 2: 1–6.
• Mahendradhata Y, Probandari A, Ahmad RA, et al. The incremental cost-effectiveness of engaging private practitioners to refer tuberculosis suspects to DOTS services in Jogjakarta, Indonesia. Am J Trop Med Hyg 2010; 82(6): 1131–1139.
• Asyary A, Purwantyastuti, Eryando T, et al. Perceived of healthcare utilization by adult pulmonary tuberculosis patients for their children in Yogyakarta. Asian J Epidemiol 2017; 10(2): 70–75.
• Pae C-U. Why systematic review rather than narrative review? Psychiatry Investig 2015; 12(3): 417–419.