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2014 | 4 | 1 | 88-94
Article title

Haematological changes among construction workers exposed to cement dust in West Bengal, India

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EN
Abstracts
Purpose: This study measured haematological parameters in construction workers exposed to cement dust, silica and other hazardous materials. This was done in order to identify a simple, readily available, and cost effective screening test that could help to identify the presence of disease and its severity in workers potentially related to their work space. Materials and methods: The study was composed of 150 construction workers and 52 participants in an unexposed control group, with ages ranging from 15-60 years. Blood samples were collected from each participant and percentage of haemoglobin, total RBC count, WBC count, platelet count, and different RBC indices were analyzed. Results: The haemoglobin concentration, PCV, and MCV decreased significantly, but the MCHC and eosinophil counts increased significantly in comparison to the control group, though the increase in the monocyte count was not significant. No significant changes in haematological parameters with a year of exposure have been found. However, the percentage of prevalence of anaemia on the basis of haemoglobin concentration and PCV value were higher in construction workers in comparison to members of the control group. Conclusion: This study recommends that construction workers working in hazardous environments must support health education and should regularly use protective devices in their workplace. They must also have regular medical checkups, which might help detect disease in early stages.
Year
Volume
4
Issue
1
Pages
88-94
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References
  • Short S, Petsonk EL. Non fibrous inorganic dusts. Harbur P. Schenker MB, Balmes JR, editors. Occupational and environmental respiratory disease. London (UK), Mosby,1996. p 356.
  • Coates TD, Bachner RL. Leucocytosis & Leukopenia. In: Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, editors. Hematology Basic Principles & Practice. 1st ed. New York (NY), Churchill Livingstone, 1991. p 552.
  • Jude LC, Sasikala K, Kumar RA, Sudha S, Raichel J. Haematological and cytogenic studies in workers occupationally exposed to Cement dust. Int. J. Hum. Genet 2002; 2:95-99.
  • Fatima SK, Prabhavathi PA, Padmavathi P, Reddy PP. Analysis of chromosomal aberration in men occupationally exposed to cement dust. Mutat Res 2001 Feb; 490(2):179-86.
  • Dacie J and Lewis SM. Practical Haematology, 6th ed. London, UK, Churchill, 1986.
  • Van Kampen EL, Zulstra WJ. Standardization of Haemoglobinometry: The haemoglobin Cyanide method. Clin Chem Acta 1961;6:352 – 544.
  • Pongpaew P, Tumgtrongchitr R, Tawprasrt S.Vitamins, electrolytes, hematological status of urban construction site workers in Bangkok. Asia Pacific J Clin Nutr. 1993;2:135-40
  • Liaqat I, Arshad M, Arshad R, Arshad N. Exposure to textile chemicals leads to microcytic anaemia and hypersensitivity in textile workers. Pakistan J Zool. 2009 May; 41(5):381 - 7.
  • Kokila S, Bhuvaneswari V, Jeyanthi GP. Mutagenicity of zinc electroplating industry effluents and genotoxicity in lymphocytes of zinc electroplating industry workers. J. Indust Pollut Contr. 2005;5:213 – 6.
  • Pradip K, Gupta YG, Vishal T, Shakti T, Ajay S. Haematological and biochemical abnormalities in Cirrhinus mrigala (Harm) induced by lead. J Ecophysiol Occup Health. 2005; 5: 213 – 6.
  • Singhi MK, Menghani PR, Gupta LK, Kachhawa D, Bansal M. Occupational contact dermatitis among the traditional ‘tie‘ and ‘dye’ cottage industry in Western Rajasthan. Indian J Dermatal Venereol Leprol. 2005 Sep-Oct; 71: 329 – 32.
  • Divya Priya S, Suja S. The effect of cement dust exposure on hematological and cytogenic studies of cement workers. RJPBCS. 2012 Jan - Mar; 3 (1): 615 – 20.
  • Barton CC, Ganey PE, Roth RA. Lipopolysaccharide augments aflatoxin B(1)–Induced liver injury through neutrophil – dependent and independent mechanisms. Toxicol Sci. 2000 Nov; 58(1): 208 – 15.
  • Meo SA, Rasheed S, Khan MM, Shujauddin S, Al-Tuwaijri AS. Effect of cement dust exposure on phagocytic function of polymorphonuclear neutrophils in cement mill workers. Int J Occup Med Environ Health. 2008; 21(2):133-9.
  • Gleich GJ. Mechanism of eosinophil associated inflammation. J Allergy Clin Immunol. 2000 Apr; 105(4): 651 – 63.
  • EL Banna SM, Mahdi WK, Ali BA, Raouf MM. Role of nerve growth factor in allergic and inflammatory lung diseases. J Microbiol Immunol Infect. 2006 Dec; 39(6):444- 51.
  • Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, Luttmann W, Renz H, Virchow JC Jr. The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. J Exp Med. 2003 Aug 4; 198(3):455-67.
  • Goyarts T, Dänicke S, Tiemann U, Rothkötter HJ. Effect of the Fusarium toxindeoxynivalenol (DON) on IgA, IgM and IgG concentrations and proliferation of porcine blood lymphocytes. Toxicol In Vitro. 2006 Sep; 20(6):858-67.
  • Tulinska J, Jahnova E, Dusinska M, Kuricova M, Liskova A, Ilavska S, Horvathova M, Wsolova L, Kyrtopoulos SA, Collins A, Harrington V, Fuortes L. Immunomodulatory effects of mineral fibres in occupationally exposed workers. Mutat Res. 2004 Sep 3; 553(1-2):111- 24.
  • Ali AA Sahb. Hematological assessment of gasoline exposure among petrol filling Workers in Baghdad. J Fac Med Baghdad. 2011May; 53(4): 396 - 400.
  • Nieters A, Deeg E, Becker N. Tobacco and alcoholic consumption and risk of lymphoma: results of a population – based case control study in Germany. Int J Cancer. 2006 Jan; 118(2):422 – 30.
  • Mojiminiyi FBO, Merenu I.A, Ibrahim MTO, Nioku CH, Ibrahim MTO. Regression Formulae for predicting Hematologic and liver functions from years of exposure to cement dust in cement Factory Workers in Sokoto, Nigeria. Afr J Biomed Res. 2007 Sep;10:235 - 40.
  • Guguloth MR, Sambanaik A, Srinivasnaik L, Mude J. The effect of cement dust exposure on haematological parameters of cement factory workers in Nalagonda, Andhrapradesh. IJOART. 2012 Oct; 1(5):1 -7.
  • Redlich CA. Pulmonary fibrosis and interstitial lung diseases. In: Occupational and environmental respiratory disease. Edited by Philip, Harber, Marc, B. Schenker and John, R. Balmes, Mosby London. 1996; p. 216 -22.
  • Hauser R, Elreedy S, Hoppin JA, Christiani DC. Upper airway response in workers exposed to fuel oil ash: nasal lavage analysis. Occup Environ Med. 1995 May;52(5):353 -8.
Document Type
Publication order reference
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YADDA identifier
bwmeta1.element.desklight-6c42ade7-54f5-476e-926a-efcf2ad22c21
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