This article show's life of father Agathon and his work for the monophisitic Church of Alexandria in the history background of he’s times. Agathon was a head of monophisitic Church of Egypt. He went in patriarch’s throne in 661. Agathon was a second patriarch, after Benjamin I (622-661), who reigned under Muslim domination in Egypt. Agathon continued efforts of he’s predecessor in rebuilding and consolidation of monophisitic Church of Alexandria. This patriarch, like his predecessor, was a monk. He had educated in Sancti Macarius monastery. Eighteen patriarchs of Egypt came from this monastery. As disciple of this monastery Agathon have expanded it so numbers of monks have increased.