The importance of education can never be underplayed in any society as it is the most potent weapon given to man to transform, change and liberate him and society from the slavery of ignorance and backwardness. Education allows man to attain a rapid development in all ramifications. It should be known from the outset that universities in Africa are moulded on the foundation and systemic structure of the Western ideologies. There are salient multi-faceted and multi-dimensional barriers towards the pursuit of higher education in Africa. The aim of this paper is to examine the challenges of higher education in Africa, which hinders its process of producing a body of knowledge that will elevate the human condition and posit it for all-round development.