Mycolic Acids as Markers of Osseous Tuberculosis in the Neolithic Skeleton from Kujawy Region (Central Poland)

• Authors: Beata Borowska-Strugiń , Magdalena Druszczyńska , Wiesław Lorkiewicz , Rafał Szewczyk , Elzbieta Ządzińska
• Languages of publication: EN

Abstracts

EN

The subject of analysis is the male skeleton from a double burial of the Globular Amphora Culture, derived from the Neolithic site at Brześć Kujawski in Kujawy region (central Poland). Within the spine of the individual advanced lesions are observed (destruction of the vertebral bodies, symptoms of the periostitis in the thoracic region) which are characteristic of skeletal tuberculosis. To check whether the observed morphological changes resulted from infection with Mycobacterium tuberculosis (M.tb), the bone material was tested positively for the presence of mycolic acids, the specific components of the cell wall of pathogenic M.tb bacilli, by mass spectrometry.

Keywords

EN

mycolic acids; paleopathology; Neolithic

• Publisher: Sciendo
• Journal: Anthropological Review
• Year: 2014
• Volume: 77
• Issue: 2
• Pages: 137-149

Dates

received

2013-12-19

accepted

2014-04-24

online

2014-07-15

Contributors

author

Beata Borowska-Strugiń

• Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland

author

Magdalena Druszczyńska

• Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland

author

Wiesław Lorkiewicz

• Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland

author

Rafał Szewczyk

• Department of Biotechnology and Industrial Microbiology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland

author

Elzbieta Ządzińska

• Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland

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Identifiers

DOI

10.2478/anre-2014-0012