Cytisine parameters measured in the 1.5 Tesla magnetic field

• Authors: Zuzanna Bober , Sabina Galiniak , Dawid Leksa , Klaudia Dynarowicz , David Aebisher , Elżbieta Ostańska , Anna Czmil , Piotr Bar , Dorota Bartusik-Aebisher , Piotr Tutka
• Languages of publication: EN

Abstracts

EN

Introduction. Cytisine, Cytisinum (C11H14N2 O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substances.

Keywords

EN

cytisine; desmoxan; magnetic resonance imagin; tabex

• Publisher: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
• Journal: European Journal of Clinical and Experimental Medicine
• Year: 2020
• Issue: 1
• Pages: 16-19

Contributors

author

Zuzanna Bober

• Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland

author

Sabina Galiniak

• Department of Biochemistry and General Chemistry, Medical College of Rzeszów University, Rzeszów, Poland

author

Dawid Leksa

• Rzeszów Center for Vascular and Endovascular Surgery, Rzeszów, Poland

author

Klaudia Dynarowicz

• Natural Sciences College of Rzeszów University, Rzeszów, Poland

author

David Aebisher

• Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland

author

Elżbieta Ostańska

• Clinical Department of Pathomorphology, Clinical Hospital No. 1, Rzeszów, Poland

author

Anna Czmil

• Department of Computer Sciences, Rzeszów University of Technology, Rzeszów, Poland

author

Piotr Bar

• Clinical Department of Pathomorphology, Clinical Hospital No. 2, Rzeszów, Poland16-19

author

Dorota Bartusik-Aebisher

• Department of Biochemistry and General Chemistry, Medical College of Rzeszów University, Rzeszów, Poland

author

Piotr Tutka

• Department of Pharmacology, Medical College of University of Rzeszow, Rzeszów, Poland

Identifiers

DOI

10.15584/ejcem.2020.1.3