PL EN


2018 | 1 | 28-33
Article title

The significance of NGAL and KIM-1 proteins for diagnosis of acute kidney injury (AKI) in clinical practice

Content
Title variants
Languages of publication
EN
Abstracts
EN
Introduction. Despite advances in medical care AKI (acute kidney injury) is associated with high morbidity and mortality. The lack of adequate early renal injury biomarkers is often a problem for an early AKI diagnosis. In recent years, numerous scientific studies have been carried out which reveal new urine and serum markers to assess the period of the kidney injury before revealing its late clinical effects. In most clinical settings, AKI is due to acute renal tubular necrosis which results in protein accumulation in urine. Determination of the concentrations of proteins such as NGAL (neutrophil gelatinase-associated lipocalin) and KIM-1 (kidney injury molecule-1) are of great significance in the diagnosis of AKI. Aim. The purpose of the study was to review the literature about significance of NGAL and KIM-1 proteins for diagnosis of acute kidney injury (AKI) in clinical practice. Materials and method. Analysis of Polish and foreign literature.
Year
Issue
1
Pages
28-33
Physical description
Contributors
author
  • Department of Biochemistry, Institute of Clinical and Experimental Medicine, Faculty of Medicine, University of Rzeszow, Poland
  • Department of Biochemistry, Institute of Clinical and Experimental Medicine, Faculty of Medicine, University of Rzeszow, Poland
  • Department of Human Immunology, Faculty of Medicine, University of Rzeszow, Poland
  • Faculty of Medicine, University of Rzeszow, Poland
  • St’Queen Jadwiga Clinical District Hospital No. 2 in Rzeszow, Poland
References
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.mhp-7e26789f-8d88-4cff-8db3-db7e5f9d4566
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.