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2019 | 9 | 1-2 | 72-82

Article title

Deprywacja snu jako metoda leczenia depresji

Content

Title variants

EN
Sleep deprivation as a method in the treatment of depression

Languages of publication

PL

Abstracts

Istnieje wiele doniesień na temat zaburzeń rytmów dobowych w przebiegu chorób afektywnych. Rytmy okołodobowe dotyczą wydzielania wielu neuroprzekaźników (w tym noradrenaliny, serotoniny, dopaminy) oraz hormonów, które są istotne z punktu widzenia leczenia farmakologicznego w psychiatrii. Chronoterapia polega na kontrolowanej ekspozycji na bodźce środowiskowe, które wpływają na rytmy biologiczne i dają zamierzony efekt terapeutyczny. Najlepiej poznaną metodą chronoterapii jest deprywacja snu (sleep deprivation, SD), która posiada wielokierunkowy mechanizm działania, przynosi szybki efekt przeciwdepresyjny, jest metodą skuteczną, posiada niewiele przeciwwskazań i skutków ubocznych. Niestety bardzo często obserwuje się gwałtowne pogorszenie po epizodzie snu, gdy nie stosuje się metod podtrzymujących efektu terapeutycznego SD. Obecnie najbardziej zalecanym schematem jest łączenie całkowitej deprywacji snu (total sleep deprivation, TSD) z przesunięciem fazy snu (sleep phase advance, SPA), terapią jasnym światłem (bright light therapy, BL, LT) oraz farmakoterapią. Takie postępowanie ma udowodnioną skuteczność krótko- i długoterminową, może mieć korzystny efekt w leczeniu depresji lekoopornej.
EN
There are many reports on the disturbances of circadian rhythms in the course of affective disorders. Circadian rhythms influence secretion of many neurotransmitters (including norepinephrine, serotonin, dopamine) and hormones, which are important from the point of view of pharmacological treatment in psychiatry. Chronotherapy involves controlled exposure to environmental stimuli that affect biological rhythms and produce an intended therapeutic effect. Best known method of chronotherapy is sleep deprivation (SD), which has a multidirectional mechanism of action and provides a fast antidepressant effect. It is an effective method, has few contraindications and side effects. Unfortunately, very often observed rapid deterioration after an episode of sleep when it is not used methods of supporting SD therapeutic effect. Currently, the most recommended schedule is to combine total sleep deprivation (TSD), sleep phase advance (SPA), bright light therapy (BL, LT) and pharmacotherapy. Such a procedure has proven the effectiveness of short-term and long-term, can have a beneficial effect in the treatment of drug-resistant depression

Year

Volume

9

Issue

1-2

Pages

72-82

Physical description

Dates

published
2020-01-15
printed
2019-12-30

Contributors

  • Uniwersytet Medyczny w Poznaniu
  • Uniwersytet Medyczny w Poznaniu

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.mhp-bc93790a-bce8-4bb3-804f-bc83cf74a0d9
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