Risk agents related to work and amyotrophic lateral sclerosis: An occupational medicine focus

• Authors: Elpidio Maria Garzillo , Nadia Miraglia , Paola Pedata , Daniela Feola , Monica Lamberti

Abstracts

EN

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons. In recent years, in addition to several studies about genetic mechanisms leading to motor neurons damage, various epigenetic theories have been developed, involving the study of the patients’ work and lifestyle. The work aims at focusing the role of occupational exposure related to ALS by literature data analysis. Articles, selected on the basis of keywords, year of publication and topics, are related to occupational exposure, suggesting an impact on ALS onset. The literature review shows that there are still a lot of biases in the studies design, which actually do not allow to draw unequivocal conclusions.

Keywords

EN

occupational exposure; amyotrophic lateral sclerosis; occupational medicine; neurodegenerative processes; heavy metals; working adults

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2015
• Volume: 29
• Issue: 3
• Pages: 355-367

Dates

published

2016

Contributors

author

Elpidio Maria Garzillo

• Second University of Naples, Naples, Italy (Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Occupational Medicine Area)

author

Nadia Miraglia

• Second University of Naples, Naples, Italy (Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Occupational Medicine Area)

author

Paola Pedata

• Second University of Naples, Naples, Italy (Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Occupational Medicine Area)

author

Daniela Feola

• Second University of Naples, Naples, Italy (Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Occupational Medicine Area)

author

Monica Lamberti

• Second University of Naples, Naples, Italy (Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Occupational Medicine Area)

Identifiers

DOI

10.13075/ijomeh.1896.00368

Biblioteka Nauki

2177444