Isoprostanes – A novel major group of oxidative stress markers

• Authors: Marta Czerska , Marek Zieliński , Jolanta Gromadzińska

Abstracts

EN

Isoprostanes are a recently discovered group of prostaglandin isomers. Results of previous studies suggest that they can be used as oxidative stress markers, because in a number of cardiovascular, pulmonary and neurological diseases their levels in biological samples considerably increase. It has been found that people suffering from diabetes, obesity, homozygous familial hypercholesterolemia, moderate hypercholesterolemia, and smokers have higher levels of isoprostanes in urine. The same refers to patients with asthma, Alzheimer disease and Down syndrome. This paper reviews the results of relevant studies.

Keywords

EN

isoprostanes; cardiovascular; pulmonary; neurological; oxidative stress biomarkers; asbestosis

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2015
• Volume: 29
• Issue: 2
• Pages: 179-190

Dates

published

2016

Contributors

author

Marta Czerska

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis)

author

Marek Zieliński

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis)

author

Jolanta Gromadzińska

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis)

Identifiers

DOI

10.13075/ijomeh.1896.00596

Biblioteka Nauki

2177073