Cardiogenic shock induced by a high dose of intravenous morphine

• Authors: Łukasz Sein Anand , Paweł K. Korolkiewicz , Jacek Sein Anand

Abstracts

EN

Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock, and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors’ knowledge, this is the second case of a morphine-related CS reported in literature.

Keywords

EN

suicide; toxicology; opioids; cardiogenic shock; pharmacology; morphine

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2021
• Volume: 34
• Issue: 1
• Pages: 133-138

Dates

published

2021

Contributors

author

Łukasz Sein Anand

• Medical University of Gdansk, Gdańsk, Poland (Department of Clinical Toxicology)
• Pomeranian Center of Toxicology, Gdańsk, Poland

author

Paweł K. Korolkiewicz

• Medical University of Gdansk, Gdańsk, Poland (Department of Clinical Toxicology)

author

Jacek Sein Anand

• Medical University of Gdansk, Gdańsk, Poland (Department of Clinical Toxicology)
• Pomeranian Center of Toxicology, Gdańsk, Poland

Identifiers

DOI

10.13075/ijomeh.1896.01629

Biblioteka Nauki

2086176