An association between cumulative exposure to light at night and the prevalence of hyperuricemia in steel workers

• Authors: Xiaoming Li , Xianghui Xu , Yang Song , Shiyue Cui , Chao Xue , Lihua Wang , Jianhui Wu , Juxiang Yuan

Abstracts

EN

ObjectivesExposure to light at night (LAN) can disturb circadian endocrine and metabolic rhythms. Hyperuricemia (HUA) is an early-onset metabolic disorder. However, it is still not clear whether LAN exposure increases the prevalence of HUA.Material and MethodsThe authors used crosssectional data on the Beijing-Tianjin-Hebei occupational populations cohort from March–July 2017. A total of 7664 steel workers were finally selected to investigate the relationship between LAN exposure and the prevalence of HUA among steel workers. The authors collected demographic and socio-economic data, as well as information on lifestyle factors, anthropometric measures, and laboratory tests. The restricted cubic spline method was used to analyze the dose-response relationship between cumulative LAN exposure and the prevalence of HUA. Logistic regression analyses were used to fit the relationship between them.ResultsThe average age of the participants was 43.5±8.6 years; 7051 (91.7%) of them were males, 2749 (35.9%) reported to suffer from HUA, and 1241 (16.2%) were not exposed to LAN. There was a significant non-linear dose-response relationship between them. After adjustment for the confounding factors, including demographic data, lifestyle factors, etc., the lower LAN exposure was significantly associated with HUA (0–1931.7 days, OR = 1.180, and the 95% CI: 1.000–1.394; 1931.7–4343 days, OR = 1.215, 95% CI: 1.035–1.426).ConclusionsThis study revealed that a certain amount of exposure to LAN is independently related to the prevalence of HUA in steel workers in China.

Keywords

EN

uric acid; circadian rhythms; hyperuricemia; steel workers; light at night; restricted cubic spline

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2021
• Volume: 34
• Issue: 3
• Pages: 385-401

Dates

published

2021

Contributors

author

Xiaoming Li

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Xianghui Xu

• North China University of Science and Technology, Tangshan, China (Hospital)

author

Yang Song

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Shiyue Cui

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Chao Xue

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Lihua Wang

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Jianhui Wu

• North China University of Science and Technology, Tangshan, China (School of Public Health)

author

Juxiang Yuan

• North China University of Science and Technology, Tangshan, China (School of Public Health)

Identifiers

DOI

10.13075/ijomeh.1896.01648

Biblioteka Nauki

2085783