To vaccinate or not to vaccinate – BNT162b2 seroconversion rate and side effects among Polish healthcare workers

• Authors: Bartosz Siewert , Anna Szabat , Małgorzata Chądzińska-Cebula , Natalia Purpurowicz-Miękus , Piotr Sujkowski , Rafał Spachacz , Grzegorz Dworacki , Jacek Wysocki , Danuta Januszkiewicz-Lewandowska , Ewelina Gowin

Abstracts

EN

Objectives The study aimed to analyze the effect of BNT162b2 vaccination among Polish healthcare workers in terms of serologic response and adverse events. Material and Methods A questionnaire survey covered data in the period January 1–March 31, 2021 gathered in 2 hospitals in Wielkopolska, Poland. Additionally, serological analysis (SARS-CoV-2 anti-S protein IgG) was performed. Results A total of 617 medical workers were vaccinated with BNT162b2 (Comirnaty, Pfizer). Data from the questionnaires were received from all of the staff after the first and the second dose. No severe side effects were observed. The most common side effect following the first and second doses of vaccination was pain at the injection site. After the first dose, 3 (1.4 %) women aged 18–55 years, 5 women (3.9 %), and 3 men (8.3 %) aged >55 years had negative SARS-CoV-2 anti-S protein IgG result. After the second dose, all those who agreed to have antibodies tested responded to vaccination with positive SARS-CoV-2 anti-S protein IgG results. Conclusions Vaccination tolerance was good in the studied population; no severe side effects were observed. After the second dose, all tested healthcare workers responded to vaccination with antibody production.

Keywords

EN

vaccination; healthcare; side effect; COVID-19; SARS-CoV-2; BNT162b2

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2022
• Volume: 35
• Issue: 6
• Pages: 761-766

Dates

published

2022

Contributors

author

Bartosz Siewert

• Poznan University of Medical Sciences, Poznań, Poland (Department of Preventive Health)
• Children’s Hospital in Poznan, Poznań, Poland

author

Anna Szabat

• Poznan University of Medical Sciences, Poznań, Poland (Department of Preventive Health)
• Children’s Hospital in Poznan, Poznań, Poland

author

Małgorzata Chądzińska-Cebula

• Children’s Hospital in Poznan, Poznań, Poland

author

Natalia Purpurowicz-Miękus

• Children’s Hospital in Poznan, Poznań, Poland

author

Piotr Sujkowski

• Children’s Hospital in Poznan, Poznań, Poland

author

Rafał Spachacz

• Hospital in Slupca, Słupca, Poland

author

Grzegorz Dworacki

• Poznan University of Medical Sciences, Poznań, Poland (Department of Clinical Immunology)

author

Jacek Wysocki

• Poznan University of Medical Sciences, Poznań, Poland (Department of Preventive Health)
• Children’s Hospital in Poznan, Poznań, Poland

author

Danuta Januszkiewicz-Lewandowska

• University of Medical Sciences, Poznań, Poland (Department of Oncology – Hematology and Bone Marrow Transplantation Poznan)

author

Ewelina Gowin

• Poznan University of Medical Sciences, Poznań, Poland (Department of Preventive Health)
• Children’s Hospital in Poznan, Poznań, Poland

Identifiers

DOI

10.13075/ijomeh.1896.01887

Biblioteka Nauki

2152979