Zoonotic bacteria in the vicinity of animal farms as a factor disturbing the human microbiome: a review

• Authors: Anna Kozajda , Emilia Miśkiewicz , Karolina Jeżak

Abstracts

EN

This review is aimed at summarizing the current state of knowledge about the relationship between environmental exposure to the bioaerosol emitted by intensive livestock farming and changes in the microbiome of people living in livestock farm vicinity. The PubMed, Scopus and Web of Science databases were searched by crossing keywords from the following 3 groups: a) “livestock,” “animal farms,” “animal breeding”; b) “microbiome,” “resistome”; c) “livestock vicinity,” “farm vicinity,” “neighborhoods and health” in 2010–2022. Literature screening did not reveal any paper related to the full microbiome composition in the population studied. In the study, the authors included 7 papers (5 from the Netherlands, 1 from the USA, and 1 from China). The studies confirmed the carriage of Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), livestock-associated MRSA (LA-MRSA MC398) and multidrug-resistant S. aureus (MDRSA) in the nasal microbiome of adults and children living within 500–2000 m from a livestock farm. Clostridium difficile, including LA-ribotype RT078 carriage, was detected in the intestinal microbiome of adults living within 500–1000 m. Extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae were confirmed in the intestinal microbiome of adults living within 500–6200 m. Knowledge on the composition of the microflora of people living in livestock farm vicinity is insufficient to conclude about changes in the microbiome caused by the environmental emission of bioaerosol. The carriage prevalence of the LA-bacteria, including both strains with antimicrobial resistance and antimicrobial resistance genes, confirms the presence of zoonotic bacteria in the human microflora in populations without occupational contact with animals. It cannot be ruled out that zoonotic bacteria, as a component of the microbiome, have a negative impact on people’s health.

Keywords

EN

environmental exposure; microbiome; livestock; antibiotic resistance microorganisms; ARG; farm vicinity

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2024
• Volume: 37
• Issue: 2
• Pages: 138-152

Dates

published

2024

Contributors

author

Anna Kozajda

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Chemical Safety, Biological Safety Unit)

author

Emilia Miśkiewicz

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Chemical Safety, Biological Safety Unit)

author

Karolina Jeżak

• Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Chemical Safety)

Identifiers

DOI

10.13075/ijomeh.1896.02003

Biblioteka Nauki

31341039