Neonatal lupus in an infant with maternal history of Jessner’s lymphocytic infiltrate

• Authors: Bhumesh Kumar Katakam , Arunima Dhabal , Narsimha Rao Netha Gurram , Sudharani Chintagunta

Abstracts

EN

Introduction and aim. Neonatal lupus erythematosus (NLE) is a rare autoimmune condition occurring in infants born to mothers with circulating antinuclear autoantibodies, particularly anti-Ro and anti-La. It presents with a characteristic cutaneous rash, which may be accompanied by systemic manifestations. The condition is mostly self-limited, although congenital heart block, if present, is irreversible. We report a rare case of cutaneous NLE in an infant of a mother with a prior history of Jessner’s lymphocytic infiltration of skin (JLIS), which is arguably a variant of cutaneous lupus erythematosus (LE). Description of the case. This report concerns an infant presenting with cutaneous manifestations of NLE, without any systemic involvement. The mother was asymptomatic, but had been previously diagnosed with JLIS. The diagnosis of NLE was made based on serological results from both the infantile and maternal blood. Conservative management was sufficient to achieve complete resolution. Conclusion. The case underscores the importance of considering NLE in infants presenting with annular rash, even in asymptomatic mothers with no known rheumatic disease. It also suggests that JLIS may belong to the same spectrum as LE, rather than being a separate entity. This warrants careful prenatal monitoring in mothers with a concurrent or prior diagnosis of JLIS.

Keywords

EN

cutaneous lupus erythematosus; Jessner’s lymphocytic infiltrate; neonatal lupus

• Publisher: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
• Journal: European Journal of Clinical and Experimental Medicine
• Year: 2024
• Issue: 4
• Pages: 961-964

Dates

published

2024

Contributors

author

Bhumesh Kumar Katakam

• Department of Dermatology, Venereology and Leprosy, Gandhi Medical College and Hospital, Secunderabad, India

author

Arunima Dhabal

• Department of Dermatology, Venereology and Leprosy, Jagannath Gupta Institute of Medical Sciences and Hospital, Kolkata, India

• https://orcid.org/0000000325536453

author

Narsimha Rao Netha Gurram

• Department of Dermatology, Venereology and Leprosy, Gandhi Medical College and Hospital, Secunderabad, India

author

Sudharani Chintagunta

• Department of Dermatology, Venereology and Leprosy, Gandhi Medical College and Hospital, Secunderabad, India

Identifiers

DOI

10.15584/ejcem.2024.4.1

Biblioteka Nauki

62645121