Full-text resources of CEJSH and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


2018 |

Article title

Diet supplementation with flaxseed stimulates gut metabolism in mice

Content

Title variants

Languages of publication

EN

Abstracts

EN
Essential polyunsaturated fatty acids (PUFAs) in the feed may affect the gastrointestinal microbiota. The present study investigated the effect of 35-day supplementation of mice diet with 5% concentration of high-ω-3 PUFAs in flaxseed with focus on intestinal metabolism of mice. Capillary isotachophoresis method was used for the assessment of the level of organic acids in the gut material and faeces. Supplementation of flaxseed increased the level of organic acids in the caecum (acetic, propionic, butyric and valeric acids) and faeces (lactic, acetic, butyric acids). The most significant effect was observed on day 28 of flaxseed supplementation. The investigated additive had a stimulatory effect on intestinal metabolism and fermentation activity of beneficial bacteria.

Keywords

Contributors

  • Department of Anatomy, Histology and Physiology, Institute of Physiology, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic
  • Department of Anatomy, Histology and Physiology, Institute of Physiology, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic
  • Department of Anatomy, Histology and Physiology, Institute of Physiology, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic
  • Department of Anatomy, Histology and Physiology, Institute of Physiology, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic

References

  • Axling, U., Olsson, C., Xu, J., Fernandez, C., Larsson, S., Ström, Ahrné, S., Holm, C., Molin, G., Berger, K. (2012). Green tea powder and Lactobacillus plantarum affect gut microbiota, lipid metabolism and inflammation in high-fat fed C57BL/6J mice. Nutrition & Metabolism, 9, 105. https://doi.org/10.1186/1743-7075-9-105
  • Borovská, D., Nemcová, R., Gancarčíková, S., Koščová, J. (2013). The synbiotic effect of lactobacilli and flaxseed on selected intestinal microflora and organic acid levels in weaned piglets. Microbiology, 2(10), 82–86.
  • Generoso de Vasconcelos, S., Rodrigues, N.M., Trindale, L.M., Paiva, N.C., Cardoso, V.N., Carneiro, C.M., Ferreira, De Matos, A.D., Faria, A.M.C., Maioli, T.U. (2015). Dietary supplementation with omega-3 fatty acid attenuates 5-fluorouracil induced mucositis in mice. Lipids in Health and Disease, 14(54), 1–10. https://doi.org/10.1186/s12944-015-0052-z
  • Hekmatdoost, A., Feizabadi, M.M., Djazayery, A., Mirshafiey, A., Eshraghian, M.R., Yeganeh, S.M., Sedaghat, R., Jacobson, K. (2008). The effect of dietary oils on caecal microflora in experimental colitis in mice. Indian Journal of Gastroenterology, 27, 186–189.
  • Kiarie, E., Nyachoti, C.M., Slominski, B.A., Blank, G. (2007). Growth performance, gastrointestinal microbial activity and nutrient digestibility in early-weaned pigs fed diets containing flaxseed and carbohydrase enzyme. Journal of Animal Science, 85, 2982–2993. https://doi.org/10.2527/jas.2006-481
  • Martinez, F.A.C., Balciunas, E.M., Converti, A., Cotter, P.D., Oliveira, R.P.S. (2013). Bacteriocin production by Bifidobacterium spp.: A review. Biotechnology Advances, 31, 482–488. https://doi.org/10.1016/j.biotechadv.2013.01.010
  • Nemcová, R., Borovská, D., Koščová, J., Gancarčíková, S., Mudroňová, D., Buleca, V., Pistl, J. (2012). The effect of supplementation of flax-seed oil on interaction of Lactobacillus plantarum – Biocenol™ LP96 and Escherichia coli O8:K88ab:H9 in the gut of germ-free piglets. Research in Veterinary Science, 93, 39–41. https://doi.org/10.1016/j.rvsc.2011.07.031
  • Serban, D.E. (2014). Gastro-intestinal cancers: influence of gut microbiota, probiotics and prebiotics. Cancer Letters, 345(2), 258–270. https://doi.org/10.1016/j.canlet.2013.08.013
  • Wong, J.M., Jenkins, D.J. (2007). Carbohydrate digestibility and metabolic effects. Journal of Nutrition, 137, 2539–2546. https://doi.org/10.1093/jn/137.11.2539S
  • Yu, H-N., Zhu, J., Wen-Sheng, Pan, W-S., Shen, S-R., Shan, W-G., Das, U.N. (2014). Effects of fish oil with a high content of n-3 polyunsaturated fatty acids on mouse gut microbiota. Archives of Medicinal Research, 45(3), 195–202. https://doi.org/10.1016/j.arcmed.2014.03.008

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.ojs-doi-10_24917_25438832_3supp_9
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.