The necessity to reexamine the definition of the human embryo adopted by the CJEU

• Authors: Piotr Rieske , Błażej Kmieciak

Abstracts

EN

In 2022, several publications have appeared which require legal and ethical reflection. These are the works of Sheng Ding, Magdalena Żernicka Goetz, Jacob Hann, and Vincent Pasque. They concern two methods of obtaining mammalian embryos without the use of an ovum. One is reprogramming, „going back” to the state of totipotency (zygote). The second one is self-organization into the organism of cells from which it seemed, until 2022, that any cells of the organism could arise, but not the organism or the teratoma. In the second case, the embryos have reached the stage that previously required implantation into the uterus. We propose to reconsider the CJEU embryo definition in an attempt to avoid the instrumental use of human embryos because the current definition is likely to be used for that purpose , especially by means of the article presented by the Sheng Ding team. The authors of this letter (biotechnologist and bioethicist) have doubts concerning the legal status of human embryos, which can probably be obtained after using the data from these publications (1–4). These doubts result from the fact that the reports that are currently reaching the world of science in connection with the above-mentioned research, demonstrate that it is theoretically possible to create human embryos that will not be properly protected by law. The most controversial studies have been conducted on animals. Nonetheless, the project to commence the production of human embryos, for the purpose of using them as 3D-printing organs (albo 3D-printed organs) has already been established (5). The CJEU in the Oliver Brüstle v. Greenpeace eV. case defined the human embryo as follows: “A human embryo is any egg cell, from its fertilization stage onwards, any unfertilized egg cell into which a nucleus derived from a mature human cell has been implanted, and any unfertilized human egg cell that has been stimulated to divide and further develop through parthenogenesis” (6).

• Publisher: Uniwersytet Opolski. Redakcja Wydawnictw Wydziału Teologicznego
• Journal: Family Forum
• Year: 2022
• Volume: 12
• Pages: 353-356

Dates

published

2022

Contributors

author

Piotr Rieske

• Medical University of Lodz

• https://orcid.org/0000000229700970

author

Błażej Kmieciak

• Medical University of Lodz

• https://orcid.org/0000000263471796

References

• Amadei, G., Handford, C.E., Qiu, C. et al. Synthetic embryos complete gastrulation to neurulation and organogenesis. Nature (2022). https://doi.org/10.1038/s41586-022-05246-3
• Shadi Tarazi, Alejandro Aguilera-Castrejon, Carine Joubran, et al. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs, Cell, Volume 185, Issue 18, 2022, Pages 3290-3306.e25,
• https://doi.org/10.1016/j.cell.2022.07.028.
• Thi Xuan Ai Pham, Amitesh Panda, Harunobu Kagawa, et al. Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells, Cell Stem Cell, Volume 29, Issue 9, 2022, Pages 1346-1365.e10, https://doi.org/10.1016/j.stem.2022.08.001.
• Hu, Y., Yang, Y., Tan, P. et al. Induction of mouse totipotent stem cells by a defined chemical cocktail. Nature (2022). https://doi.org/10.1038/s41586-022-04967-9
• This startup plans to create realistic human embryos | MIT Technology Review
• Ruling Oliver Brüstle v Greenpeace e.V. Judgment in Case C-34/10 Oliver Brüstle v Greenpeace e.V. Court of Justice of the European Union, PRESS RELEASE No 112/11 Luxembourg, 18 October2011, https://curia.europa.eu/juris/document/document.jsf;jsessionid=E1351BF284309F434E0712E06BC8A966?text=&docid=111402 =&pageIndex=0&pageIndex=0&doclang=0&doclang=0 = lst & directory = & occ = first & part = 1 & cid = 2927462

Identifiers

DOI

10.25167/FF/4891

Biblioteka Nauki

19322803