BNCT jako obiecująca metoda walki z nowotworem

• Authors: Marta Marszewska

Title variants

EN

BNCT as a promising tumoricidal modality

Abstracts

EN

Boron Neutron Capture Therapy as a tumoricidal modality features selective destruction of tumor cells. It is based on a nuclear reaction which occurs when 10B, accumulated in a cancer cell, is irradiated with thermal neutrons with appropriately selected energy. This therapy is a promising method which allows treatment of tumors that are difficult to operate due to their location, spatial distribution or resistance to traditional methods of therapy. It gives the chance to cure gliomas, head & neck cancer, and above all brain tumors. The success of this therapy depend mainly on improvements in the boron delivery agents, including their pharmacology and intracellular targeting as well as an accurate measurement of the deposited radiation dose. Paralleled by advances in radiobiology, chemistry and dosimetry it is possible to improve the therapy to meet clinical requirements, which gives the opportunity to development and implementation in medical practice. The article presents an outline of current review of BNCT. Several important aspects such as the physical, chemical basics and related challenges are discussed. Moreover, a brief review of the neutron sources used at BNCT clinics and R&D centers is provided.

Keywords

EN

BNCT; neutron radiation; ¹⁰B isotope

• Publisher: Fundacja PSC
• Journal: Alcumena. Pismo Interdyscyplinarne
• Year: 2020
• Issue: 3(3)
• Pages: 5-18

Dates

published

2020

Contributors

author

Marta Marszewska

• Politechnika Gdańska

• https://orcid.org/000000032046653X

References

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Identifiers

DOI

10.34813/psc.3.2020.1

Biblioteka Nauki

51783081