The article presents the results of research of 99 companies operating in Łodz region. The main objective of the research was to analyze companies behavior in commercialization process. Many aspects of commercialization were discovered, for example: innovation assessment, intellectual property protection, financing, commercialization strategies. The research shows that companies in Łodz create region are not innovative and they lack ability to create and implement innovations to the market. Most of the don’t creat innovations, don’t cooperate with R&D institutions, don’t use EU financial resources that are available for innovation.