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1

Signal Decoding Systems in the Mechanistic Theory of Explanation

100%

Rzepiński T.

Filozofia Nauki

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2014

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vol. 22

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issue 3

81-104

PL

The article discusses the mechanistic account of explanation and uses it to pro-pose a novel description of signal decoding systems (SDS) that occur in living or-ganisms. The considerations are based on examples taken from the field of immu-nology. The results may be used in the analysis of decoding systems in computer sci-ence.

2

Epistemological Controversies over Randomized Controlled Trials Subgroup Analysis

100%

Rzepiński T.

Filozofia Nauki

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2016

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vol. 24

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issue 4

73-94

PL

Subgroup analysis is one of the methods used in contemporary methodology of medicine for assessing the effects of undertaken therapy. It is often claimed that researchers who use the method overestimate its epistemic value. The main purpose of this paper is to analyze the credibility of conclusions formulated on the basis of subgroup analysis. Its findings will help to better understand the epistemological limitations of this method as well as to clarify its function in clinical trials.

3

Empirical Evidence in a Process of Clinical Decision Making

100%

Rzepiński T.

Filozofia Nauki

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2012

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vol. 20

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issue 3

13-33

PL

The subject of this article is to discuss epistemological issues related to the pro-cess of obtaining empirical evidence in medicine. This paper will present how N. Cartwright, J. Worrall and P. Urbach describe the function of the randomisation pro-cedure in this process. Based on these findings, it will be possible to define an alter-native method of obtaining empirical evidence for the purpose of making clinical decisions. This method involves data analysis using the Rough Set Theory proposed by Z. Pawlak. By applying this method, a deterministic algorithm for making clinical decisions can be formulated. Being an interesting alternative to statistical approaches that dominate in medicine, the RST method generates specific epistemological problems. Therefore, it seems to constitute an interesting subject of analysis for philosophers of science.

4

Functional-Causal Explanation and Its Role in Designing Pharmacological Cardioprotective Therapies

100%

Rzepiński T.

Filozofia Nauki

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2013

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vol. 21

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issue 3

99-121

PL

The purpose of the paper is to determine the structure of the functional explanations given in the process of designing pharmacological therapies in biological and medical sciences. The article shows that neither the classical models of functional explanation (presented by Hempel and Nagel) nor Cummins's functional analysis provide an adequate account. A brief discussion of these models becomes the point of departure for suggesting a functional-causal explanatory model (FP). The model is put to use in a reconstruction of the pharmacological cardioprotective therapy project.

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4 Rzepiński T.

Signal Decoding Systems in the Mechanistic Theory of Explanation

Epistemological Controversies over Randomized Controlled Trials Subgroup Analysis

Empirical Evidence in a Process of Clinical Decision Making

Functional-Causal Explanation and Its Role in Designing Pharmacological Cardioprotective Therapies