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Vznik národného podniku Biogena

100%
Sencek R. R.
DVT - Dějiny věd a techniky (History of Sciences and Technology)
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2007
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vol. 40
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issue 2
73-86
EN
The article deals with the research of a short interval, when the Ministry of Health Care tried realising an idea to establish independent pharmaceutical industry focused at the biological products. The idea of the Ministry to retain own industry was not traditional not only in relation to its own history but also to the deep-rooted character of ministries' of health care competence. Nationalised pharmaceutical industry belonged to the Ministry of Industry as regards competence. Nevertheless, it was one of the most profitable branches of the Czechoslovak industry in the given period. Therefore the Ministry of Health Care got into question of jurisdiction with the Ministry of Industry, and it prepared a project of an enterprise with the operative name Biotika that was to arch over the pharmaceutical production. The Ministry of Health Care was successful finally after many negotiations, and it established its own pharmaceutical national enterprise of the resulting name Biogena with the effect from January 1, 1950.
2
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ON THE DIVISION OF THE SECTIONS FOR THE HISTORY OF PHARMACY OF THE POLISH PHARMACEUTICAL SOCIETY

100%
Majewski J.
Analecta. Studia i Materiały z Dziejów Nauki
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2007
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vol. 16
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issue 1-2(31-32)
317-329
EN
The aim of the paper is to present the activity of the Division of the Sections for the History of Pharmacy of the Polish Pharmaceutical Society (PTFarm), established in 1964 as a successor to the Section for the History of Pharmacy, founded as an agency of the Polish Pharmaceutical Society in 1956. An overview and library search has been made of writings on the topic, mainly in 'Farmacja Polska' (Polish Pharmacy) and other journals, as well as in the series 'PAMIETNIKI' (Memoirs), published since 1999. The issues discussed in the paper have been presented at Scientific Conferences, Congresses and Symposia organized by the Section for the History of Pharmacy of the Polish Pharmaceutical Society, both in Poland and abroad. The Division of the Sections for the History of Pharmacy of the Polish Pharmaceutical Society has constituted a meeting place for historians of pharmacy from Poland and abroad. It has influenced directions of research in the particular sections and has represented the interests of historians within the Main Board of the Polish Pharmaceutical Society. The members of the Division have been active in many areas and have promoted research in the history of the profession and its ethics, as well as advocated the gathering of mementos of the activities of pharmacists.
3
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PROFESSOR JERZY TULECKI - SCIENTIST, EDUCATOR AND ACTIVIST OF THE POLISH PHARMACEUTICAL SOCIETY

80%
Umbreit M. H.
Analecta. Studia i Materiały z Dziejów Nauki
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2008
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vol. 17
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issue 1-2(33-34)
145-154
EN
The paper gives a professional profile of Prof. Jerzy Tulecki, and especially the last forty of his over ninety-years- long life, basing on the author's own reminiscences, as well as on data contained in the biographical writings. Over that period, i.e. since the 1960's, he was actively involved in teaching activities at the Pharmaceutical Faculty of the Medical School in Poznan, where he was, among other things, deputy dean of the faculty with responsibilities for student affairs, and where he excelled in his capacity as supervisor of many M.Sc. theses and Ph.D. dissertations in the field of pharmaceutics. He also had a major standing as a researcher, being the author of numerous scientific publications and patents, as well as cooperating with the pharmaceutical industry. At the same time, Jerzy Tulecki, a person of great energy, was an activist of the Polish Pharmaceutical Society, holding the posts of the Head of the Poznań Branch of the Society, as well as a member of its national board. He was responsible for many initiatives relating to the statutory activities of the Society, and was engaged in many forms of organizing the research and professional life of Polish pharmacists in the second half of the 20th century.
4

Lettuce, 'Lactuca sp.', as a medicinal plant in Polish publications of the 19th century

80%
Trojanowska A.
Kwartalnik Historii Nauki i Techniki
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2005
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vol. 50
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issue 3-4
123-134
EN
Mentions of lettuce (Lactuca sp.) that have appeared since antiquity contained similar information on its curative properties, but such properties were ascribed to different species or varieties. Apart from the wild and poisonous lettuce, also garden or common lettuce were identified as having curative action, and some publications lacked information enabling the precise identification of the lettuce in question. In the 19th century, attempts were made to put some order into the knowledge of lettuce as a medicinal plant. Information on lettuce, contained in Polish medical studies of the 19th century, points to the poisonous species 'Lactuca virosa' and the common or garden lettuce 'Lactuca sativa v. Lactuca hortensis', as being used as a medicinal plant. In that period, lettuce and especially the desiccated lactescent juice obtained from it, ' lactucarium', were considered to be an intoxicant, and were used as a sedative and an analgesic. The action of the substance was weaker than that of opium but free of the side-effects, and medical practice showed that in some cases 'lactucarium' produced better curative effects than opium. To corroborate those properties of lettuce and its lactescent juice, studies were undertaken to find the substance responsible for the curative effects of the juice. However, such studies failed to produce the expected results, and the component responsible for the curative properties of letuce was not identified. Medical practice thus had to restrict itself to the uses of the desiccated lactescent juice and extracts obtained from it. The possibility of obtaining 'lactucarium' from plants cultivated in Poland caused Polish pharmacists and physicians to take an interest in the stuff and launch their own research of lettuce and the lactescent juice obtained from it. Results of research on lettuce were published in 19th-century journals by, among others, Jan Fryderyk Wolfgang, Florian Sawiczewski and Józef Orkisz.
5
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Historia pomyłek przemysłu farmaceutycznego na przykładzie kuracji talidomidem w latach 1957-1961

80%
Płusa S.
Analecta. Studia i Materiały z Dziejów Nauki
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2012
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vol. 21
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issue 1-2(40-41)
269-324
EN
The first part of the work deals from a historical perspective with methods of treatment of nausea and vomiting, as well as other ailments connected with the initial stage of pregnancy. Also outlined there are currently known facts concerning effectiveness and security of administering the drugs described. Part two concentrates on the beginnings of the Chemie Grünenthal company and the circumstances accompanying the synthesis of talidomide, its introduction to the market and statistics concerning use of this drug in countries where it was available. Part three concerns the time when talidomide reached the United States and attempts to legalise it. The events have been described that resulted in withdrawal of this drug from the market, as well as teratogenic effects of talidomide and its pharmacological mechanism. Next part of the work brings closer the problem of legislation connected with registration of new drugs and their introduction to trade, taking into consideration the changes that occurred after the effects of talidomide treatment were revealed. Part five presents further effects of these drugs' application, both those concerning physical and mental growth of persons injured and those connected with their social status. Part six is focused on the current place of talidomid in health care, its potential capabilities, on which there is on-going research, and analogs of talidomide - levalidomide and pomalidomide. The last part of the work contains summary of the collected data and presents conclusions resulting from the whole sequence of events for the pharmaceutical industry.
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