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More than 15 years of human behaviour genetic research at the University of Warsaw

100%
Oniszczenko W.
Polish Psychological Bulletin
|
2009
|
vol. 40
|
issue 3
117-120
EN
Human behaviour genetic research has been conducted at the University of Warsaw for more than 15 years. The main focus of this work have been the origins of individual differences in temperament and other personality traits. Other areas of interest include attitudes, risk factors for human health, and posttraumatic stress disorder (PTSD). The majority of the research is conducted using quantitative genetic methods although recently work using molecular techniques has also begun to develop. This article reviews the most important directions and findings of this research.
2

MORE THAN 15 YEARS OF BEHAVIOUR GENETIC RESEARCH IN POLAND (Ponad 15 lat badan genetyki zachowania w Polsce)

100%
Oniszczenko W.
Psychologia-Etologia-Genetyka
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2009
|
vol. 20
9-16
EN
Genetic research has been conducted in Poland for more than 15 years. The main focus of this work have been the origins of individual differences in temperament and other personality traits. Other areas of interest include attitudes, risk factors for human health, and posttraumatic stress disorder (PTSD). The majority of the research is conducted using quantitative genetic methods although recently work using molecular techniques has also begun to develop. This article reviews the most important directions and findings of this research.
3

COGNITIVE ENDOPHENOTYPES IN PSYCHIATRIC DISORDERS IN THE MOLECULAR - GENETIC CONTEXT (Endofenotypy kognitywne w chorobach psychicznych w kontekscie badan genetyczno-molekularnych)

100%
Borkowska A.
Psychologia-Etologia-Genetyka
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2008
|
vol. 18
49-62
EN
Cognitive dysfunctions in psychiatric diseases, important elements of clinical picture of the illnesses, are present in major part of schizophrenic and bipolar patients and in about 50% their first degree relatives. Currently cognitive dysfunctions are known as a cognitive endophenotypes associated with the vulnerability to the illness. One of the well described cognitive endophenotype in schizophrenia and bipolar disorder are working memory dysfunctions. The molecular-genetics studies show an association of working memory disturbances in schizophrenia with the polymorphism of dopaminergic system genes, while in bipolar disorders with the polymorphism of the BDNF gene. Moreover valine allele of the D1 receptor gene is associated with the predisposition to schizophrenia, and valine allele of Val66Met of BDNF gene with predisposition to bipolar disorder. This may indicate different neurobiological mechanism of these illnesses and different genetics basis of the cognitive dysfunctions in these conditions. Polymorphism of these genes probably plays more important role in etiology of cognitive dysfunctions in mental disturbances, than in cognitive abilities in healthy subjects.
4

COGNITIVE IMPAIRMENT AND DEPRESSIVE SYMPTOMS IN OBESE SUBJECT IN MOLECULAR GENETICS CONTEXT (Dysfunkcje poznawcze oraz zaburzenia depresyjne w otylosci w kontekscie badan genetyczno-molekularnych)

100%
Bielinski M., Junik R., Tretyn A., Borkowska A.
Psychologia-Etologia-Genetyka
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2008
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vol. 18
63-70
EN
Obesity as illness of million people on all over the world is being investigated in many different clinical trials by many group of scientists. Attempt of revealing and understanding of every single factor which may influence on occurring obesity will take us many years. Obesity affects more and more adults and children each year. Most interesting trials of obesity are these which connect many disciplines. Psychological and neuropsychological data connected with biochemical, molecular and genetic results are important in completing etiopathology of obesity. Searching for endogenic substances influences on energetic balance leads to finding new rules for well known substances as cortisol or leptin. New interesting substances connected with nutrition are found also very often. For example, visfatin is compound which roles id pathogenesis of obesity is not well known. Observation of results recently published suggests that particularly interesting data are these where psychological and neuropsychological data are combination with genetic data. Genetic study among candidate genes as BDNF, DAT1, 5-HT2A indicates existence of specific polymorphism which predispose to higher BMI. Obesity is important and interesting for many medical and psychological scientists. Many aspects of obesity's problems are challenge for investigators. The results of clinical trials may give hope for obese patients for improving quality of life and better functioning in daily life.
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