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The article deals with three manuscript sources for study of the natural sciences and magic in the royal court of Wenceslas II. At first it is focused on MS Num. 513 in the Public Library in Bern called the Lapidarius et Liber de physionomia Aristotelis. This treatise was written in honour of Wenceslas II. and would be inspired by the Secretum secretorum. The next MS from the Vatican Library (Pal. Lat. 1253) contains medical treatises, supplemented with marginal notes, which relates to the use of laxatives by personalities of the Wenceslas II’s royal court. The third MS (Pal. Lat. 1253) contains treatises relating to medicine, use of talismans and other astrologicalmagical texts as well as drafts and copies of still unknown charters and letters from the time span 1285–1288.
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