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Introduction: ‘Guidelines for Diagnosis and Treatment of Malaria in India 2011’ and its earlier edition have highlighted clinical issues pertaining to conceptual, practical and challenging scenarios in diagnosis cum treatment of common malaria parasites. Purpose: To critically analyze ‘Guidelines for Diagnosis and Treatment of Malaria in India 2011’ and its edition of year 2009 for their contents, quality, comparison, drug dosage schedules, discrepancies, guiding principles and deficiencies for suggestive timely remedial measures. Materials and methods: Steps included statistical analysis of each recommended antimalarial tablet against its universally accepted drug dosage, comparative study of ‘guideline 2011’ with ‘guideline 2009’, development of new user friendly simplified tables for suggested inclusion in new/revised edition of ‘guideline 2011’ and making specific recommendations for evidence based corrective measures cum policy initiatives. Results: Critical scientific analysis of these guidelines illustrate greater need of efforts for learning, expertise, experience, research and shared knowledge based amendments thereby enabling those entrusted to deal with routine and critical care of malaria patients as well as prevention among those likely to be exposed to such infections. Conclusion: Study has underlined (a) avoidable discrepancies in therein applied principles of drug dosage and related recommended scheduling for various age groups; (b) deficiencies in the guidelines; and (c) study based recommendations for observing consensus based approach and inclusion of agreed necessary changes in amended ‘guidelines 2011’ or its new edition for better clinical decision making in the larger interest of malaria patients in India after due consideration and rigorous examination of the points of concern and suggested amendments through multidisciplinary consultative process
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