Full-text resources of CEJSH and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Results found: 2

first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  depression symptoms
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Publication available in full text mode
Content available

The study of gene polymorphisms in neurotransmitter systems (HTR1A and SLC6A3) and morphofunctional characteristics in students with depression symptoms

100%
Negasheva M., Vasileva A., Godina E.
Rocznik Lubuski
|
2018
|
vol. 44
|
issue 2a
43-55
EN
In the last decades, due to the increasing level of stress, the study of different de-pressive states and search for morpho-functional and genetic markers of depression have become important for modern society. This article is an interdisciplinary study of morpho-functional characteristics and variability of genes in the neurotransmitter systems (HTR1A and SLC6A3) in young men and women with the expression of depressive symptoms. The materials used include: morpho-functional characteristics (height, weight, body circumferences, skinfold thickness in the trunk and the extremities, and characte-ristics of cardiovascular and respiratory systems); evaluation of depression symptoms performed with the Beck questionnaire; determination of polymorphisms of the HTR1A and SLC6A3 genes for 372 students from the cities of Samara and Saransk (170 men and 202 women aged 16-23, predominantly of Russian ethnicity. The results obtained are as follows: young men and women with depression symptoms are characterized by significantly different morpho-functional characteristics (p<0.05), lower adiposity and abdominal skinfold thickness, as well as a relatively higher specific metabolic rate. No differences in the frequencies of the genotypes of the neurotransmitter systems genes (DAT1, HTR1A) were found between the groups of students with or without depression symptoms. Differences in the number of individuals with the presence of depression symptoms were revealed (p<0.05) in relation to gender: these symptoms were twice as high in women (14%) as in men (7%).
PL
W ostatnich dziesięcioleciach, ze względu na rosnący poziom stresu, badania nad różnymi stanami depresyjnymi i poszukiwanie morfofunkcjonalnych i genetycznych markerów depresji stają się coraz ważniejsze dla współczesnego społeczeństwa. Celem niniejszej pracy jest interdyscyplinarne badanie cech morfofunkcjonalnych i zmienności genów w układach neuroprzekaźników (HTR1A i SLC6A3) u młodych mężczyzn i kobiet z objawami depresyjnymi. Materiał: cechy morfofunkcjonalne (wysokość i masa, obwody ciała i grubości fałdów skórnych na tułowiu i kończynach, charakterystyka układu sercowo-naczyniowego i oddechowego); ocena objawów depresji za pomocą kwestionariusza Becka; określenie polimorfizmów genów HTR1A i SLC6A3 dla 372 uczniów z miast Samara i Sarańsk (170 mężczyzn i 202 kobiety w wieku 16 do 23 lat, głównie pochodzenia rosyjskiego). Wyniki: młode kobiety i mężczyźni z obecnością stanu depresyjnego charakteryzują się zmiennie odmiennymi cechami morfofunkcjonalnymi (p< 0, 05); mniejszą otyłością i grubością fałdów skórnych brzucha, względnie wyższą specyficzną przemianą materii. Nie stwierdzono różnic w częstości genotypów genów systemów nerwowych (DAT1, HTR1A) pomiędzy grupami uczniów z objawami depresji lub bez nich. Różnice między płciami w liczbie osób z objawami depresji zostały pokazane (p< 0, 05); objawy te były dwukrotnie wyższe u kobiet (14%) niż u mężczyzn (7%).
2
Publication available in full text mode
Content available

Occupational health: the role of demographic factors in the condition of increased risk

100%
Sitarevic A., Nesic-Tomasevic A., Nikolic D., Sofic A.
International Journal of Occupational Medicine and Environmental Health
|
2023
|
vol. 36
|
issue 2
250-262
EN
Objectives The paper analyses the impact of socio-demographic characteristics of the employees in conditions of uncertainty in the organizations. Material and Methods The study was conducted on a sample of 210 employees using the Mental Health Inventory – 38 (MHI-38), Satisfaction with life scale (SWLS), and the Center for Epidemiological Studies – Depression (CES-D). Results The results showed that female respondents had significantly higher scores on ANX (t = 2,278, p < 0.05), while male employees had higher scores on life satisfaction (t = 2.103, p < 0.05). Older employees have a higher tendency for loss of emotional-behavioral control (F = 4.427, p < 0.05). Respondents who have satisfying living standards have also higher scores on SWLS (t = 2.257, p < 0.05). Respondents who have dissatisfying living standard have higher scores on generally positive affect (t = 3.152, p < 0.01), life satisfaction (t = 3.571, p < 0.01), psychological distress (t = 2.929, p < 0.01) and loss of emotional- behavioral control (t = 2.361, p < 0.05). Employees with different levels of educational background have similar tendencies in life satisfaction, mental health, and depressive symptoms (p > 0.05). Conclusions The study showed that the specific socio-demographic profile of the employees is related to higher levels of mental health issues. Specifically, the mental health of female and older employees have been especially affected and disturbed by uncertain conditions. The results can be potentially used both in the terms of designing activities that support the mental health of the population, as well as in relation to the mental health of employees. Int J Occup Med Environ Health. 2023;36(2)
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.