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EN
The impact of health and environmental hazards, associated with the constituents of gasoline, on occupationally exposed workers has been recorded over the past few decades. However, the scientific literature on their pathogenic potential remains incomplete, which could affect the current understanding of the associated health risks. This review provides current information based on recently improved research techniques to evaluate gasoline toxicity profiles for humans. Our current knowledge provides insight into the intricate mechanism of gasoline-induced adverse effects, including the formation of reactive metabolites via bio-activation and subsequent generation of reactive oxygen species (ROS) and oxidative stress, which are involved in multiple mechanisms that are central to the aetiology of gasoline-induced toxicity. These mechanisms include covalent binding to deoxyribonucleic acid (DNA), leading to oxidative damage, tumor-suppression gene activity, and activation of pro-oncogenes. Furthermore, it results in induction of autoimmunity and local inflammatory responses, disruption of multiple neurotransmitters and immune cell function, derangement of various enzyme activities (e.g., sodiumpotassium adenosine triphosphate (Na+/K+/ATPase) activity, cytochrome P450 (CYP450), nitric oxide synthase (NOS), antioxidant enzyme activities, etc.), conjugation of bile, and non-specific cell membrane interaction, leading to damage of the membrane lipid bilayer and proteins. Available data suggests that exposure to gasoline or gasoline constituents have the potential to cause different types of illnesses. The data highlights the need to maintain safety measures via suitable research, medical surveillance, regulatory control, life style modification, early detection, and intervention to minimize exposure and manage suspected cases. They also present novel opportunities to design and develop effective therapeutic strategies against gasoline-induced detrimental effects. Int J Occup Med Environ Health 2017;30(1):1–26
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Rosnąca liczba pojazdów silnikowych na drogach powoduje wzrost zapotrzebowania na paliwa, a co za tym idzie, również na stacje paliw. Podjęty w artykule problem badawczy obejmuje analizę preferencji użytkowników samochodów osobowych przy wyborze paliw na terenie miasta Nowy Sącz. W pierwszej kolejności dokonano diagnozy rynku stacji paliw w mieście Nowy Sącz. Dalsze badania przeprowadzono wśród mieszkańców miasta posiadających co najmniej jeden pojazd samochodowy przy użyciu dobrowolnej i anonimowej ankiety. Analiza wyników wskazuje, iż olej napędowy jest najczęściej wybieranym paliwem przez użytkowników samochodów osobowych. Mieszkańcy Nowego Sącza najczęściej wybierają stacje dużych koncernów paliwowych, choć nie są przywiązani do konkretnej marki. Najważniejszymi kryteriami przy wyborze stacji są dla kierowców przede wszystkim ceny paliw, a w dalszej kolejności lokalizacja stacji i jakość paliw. Użytkownicy samochodów osobowych rzadko decydują się na paliwa niekonwencjonalne, ale chętnie zamieniliby swoje samochody na zasilane np. biopaliwami.
EN
In connection with the growing number of motor vehicles on the roads, the demand for fuels and, consequently, for fuel stations is increasing. The research problem presented in this paper includes an analysis of car users' preferences when choosing particular fuels. First, the diagnosis of the fuel station market in the city of Nowy Sacz was made. Next, some research was conducted among the city residents who owned at least one car using a voluntary and anonymous survey on the Internet. The results showed that diesel is the most frequently selected fuel by passenger car users. The inhabitants of Nowy Sacz usually choose stations of large fuel concerns, although they are not attached stations are primarily fuel prices, followed by the location of the station and the quality of fuels. Drivers of passenger cars rarely opt for unconventional fuels, but they would gladly exchange their conventional cars for those powered by biofuels.
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