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EN
The phenomenon observed in many countries for many years is an attempt to bypass the law by launching psychoactive substances on the market whose possession and sale is not regulated by the existing drug law. The number of chemically and biologically modified substances is dramatically increasing and the substances themselves are increasingly stronger and threatening people’s health and lives. Issues relating to the occurrence of New Psychoactive Substances (NPS) are the subject of increasingly in-depth analyses. In connection with the steadily increasing number of NPS and their substantial availability, there are more and more doubts about the effectiveness of the model adopted in earlier years in Europe and in individual countries, whose purpose is to subject new psychoactive substances to legal control. Based on the information presented in the article, one can assume that the reason for the development of new psychoactive substances to date was, on the one hand, the weakness of the legal regulations in force, both national and international, and on the other, specialized technical and chemical capabilities of manufacturers. Another thesis that can be put in the context of the studied subject is the statement that the phenomenon of new psychoactive substances has a high criminogenic susceptibility and is a decisively negative phenomenon, classified as the pathology of social life. In view of the above, the activities of prevention, detection and control of new psychoactive substances are important in the process of effective fight against NPS. The article does not constitute a comprehensive and complex overview of what NPS are. The aim of the study is a multifaceted analysis of the phenomenon of such substances, which will allow for a deeper understanding of the causes of such a wide scale of NPS, their diversity and ease of accessibility. Considering the above, the article attempts to stress the priority issues according to the article’s author and which are crucial in the process of universally understood NPS prevention – i.e. international cooperation, national legal regulations, and chemical analyses conducted in forensic laboratories.
PL
Celem niniejszej pracy było przygotowanie profilu chromatograficznego dwóch roślin odurzających Calea zacatechichi i Psychotria viridis. Stosowano metodę GC-MSD dla ekstraktów roślinnych otrzymanych w różnych rozpuszczalnikach organicznych: metanolu, chloroformie, toluenie. Uzyskane wyniki posłużyły do charakterystyki profilu chromatograficznego olejku pochodzącego z Calea zacatechichi oraz opracowania metody identyfikacji Psychotria viridis na podstawie modelu zbudowanego za pomocą analizy głównych składowychskładowych (Principal Component Analysis, PCA). W olejku Calea zacatechichi stwierdzono występowanie związków typowych dla rodziny Astraceae. Były to głównie izoprenoidy (terpeny), a wśród nich pochodne germakranu. Analiza GC-MS ekstraktów z Psychotria viridis wykazała obecność substancji psychoaktywnych w postaci dimetylotryptaminy (DMT) i niewielkich ilości metylotryptaminy. Analiza głównych składowych (PCA) zastosowana dla P. viridis na łączonych danych z różnych rozpuszczalników pozwoliła na stwierdzenie, że otrzymane wyniki prezentują dostatecznie wysoki stopień podobieństwa i możliwa jest identyfikacja gatunkowa rośliny opisaną metodą.
EN
The aim of this article was to elaborate the chromatographic profile of two psychoactive plants: Calea zacatechichi and Psychotria viridis. The GC-MS method, based on extraction in different organic solvents, i.e. methanol, chloroform, toluene and alkalized chloroform was applied. The obtained data was used to characterize the chromatographic profile of the oil produced from Calea zacatechichi and to elaborate a new method of identification of Psychotria viridis based on a statistical model built using PCA (Principal Component Analysis). The Calea zacatechichi oil contains chemical compounds typical for the Astraceae family, i.e. terpenes (derivatives of germacrene). GC-MS analysis of Psychotria viridis revealed presence of psychoactive substances: dimethyltriptamine (DMT) and methyltriptamine. The PCA of the Psychotria viridis on combined data from different solvents proved that the obtained data demonstrates a sufficient degree of resemblance to allow identification of species by the described method.
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