Search results

1

Clinical and videocapillaroscopic features and serum concentration of nitric oxide in patients with Raynaud’s phenomenon after Multiwave Locked System laser therapy

100%

Kuryliszyn-Moskal A., Kita J., Hryniewicz A.

Progress in Health Sciences

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2017

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vol. 7(1)

90-98

EN

Purpose: The aim of the study was the assessment of the influence of MLS laser therapy on morphological changes in nailfold videocapillaroscopy (NVC), clinical features, and the serum NO level in patients with primary and secondary Raynaud’s phenomenon (RP). Materials and methods: The analysis was performed on a group of 78 patients with RP and 30 healthy volunteers, who underwent NVC examination. NO concentration was assayed using the Griess method in blood serum before and after 3-weeks of laser biostimulation. MLS wasperformed with a Laser-M6 ASA Company device,for 3 weeks with weekend breaks, using thefollowing parameters: a frequency of 1500 Hz, adose of 25 J/cm2, and a time of 2.5 minutes on onehand. Results: After 3 weeks of MLS laser therapy, thebeneficial clinical effects manifested by a decrease of duration and number of RP attacks and degree of pain score on the visual analogue scale (VAS) in patients with primary and secondary RP. Clinical improvement after MLS laser therapy was reflected in the assessment of microcirculation disorders in NVC examination. Moreover, the tendency of normalization of NO concentration in the serum of patients with primary and secondary RP may suggest a favorable effect of laser biostimulation on the regulation of processes taking part in microcirculation disorders. Conclusions: The results showed that NVC is a useful diagnostic tool in the evaluation of dynamic microvascular involvement in RP patients. MLS laser therapy has a beneficial effect in patients with primary and secondary Raynaud’s phenomenon

2

Receiver operating characteristic analysis of the FeNO biomarker in the diagnosis of asthma

100%

Marek Biesiadecki M., Sabina Galiniak S., Dorota Bartusik-Aebisher D., David Aebisher D.

European Journal of Clinical and Experimental Medicine

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2018

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issue 4

253-258

EN

Introduction. The fraction of exhaled nitric oxide (FeNO) is used as a non-invasive biomarker that reflects inflammation in the airways. It is so versatile that it used to control asthma severity as well as to monitor response to treatment. However, the exact cut-off point of the nitric oxide level which allows one to make a precise diagnosis of asthma is unclear. Aim. To examine the possibility of using advanced statistical methods such as receiver operating characteristic for the analysis of FeNO concentrations for improving the diagnosis of asthma. Materials and methods. Receiver operating characteristic (ROC) was used for analyzing results to determine levels of nitric oxide which may be a prognostic indicator of asthma. The studied group consisted of 111 children including 69 asthmatic patients, and 42 age- and sex-matched healthy subjects. Measurement of exhaled nitric oxide was conducted in all subjects included in this study. Results. FeNO level was higher in asthmatic patients. The analysis of results showed that the cut-off point for the FeNO concentration is 11.5 ppb. Sensitivity and specificity with the FeNO level allowed us to determine a value of the diagnostic variable of FeNO concentration of 14.0 ppb. A comparison of FeNO level and sex of the subjects showed there is no correlation between these parameters of patients. Conclusions. Currently, the FeNO measurement provides complementary d

3

The influence of atmospheric circulation on the air pollution concentration and temperature inversion in Sosnowiec. Case study

75%

Widawski A.

Environmental & Socio-economic Studies

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2015

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vol. 3

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issue 2

30-40

EN

Sosnowiec is located in the Katowice Region, which is the most urbanized and industrialized region in Poland. Urban areas of such character favor enhancement of pollution concentration in the atmosphere and the consequent emergence of smog. Local meteorological and circulation conditions significantly influence not only on the air pollution level but also change air temperature considerably in their centers and immediate vicinities. The synoptic situation also plays the major role in dispersal and concentration of air pollutants and changes in temperature profile. One of the most important are the near-ground (100 m) inversions of temperature revealed their highest values on clear winter days and sometimes stay still for the whole day and night. Air temperature inversions in Sosnowiec occur mainly during anticyclone stagnation (Ca-anticyclone centre and Ka-anticyclonic ridge) and in anticyclones with air advection from the south and southwest (Sa and SWa) which cause significantly increase of air pollution values. The detailed evaluation of the influence of circulation types on the appearance of a particular concentration of pollutants carried out in this work has confirmed the predominant influence of individual circulation types on the development of air pollution levels at the Katowice region. This paper presents research case study results of the thermal structure of the near-ground atmospheric layer (100 m) and air pollution parameters (PM10, SO2, NO, NO2) changes in selected days of 2005 year according to regional synoptic circulation types. The changes in urban environment must be taken into account in analyses of multiyear trends of air temperature and air conditions on the regional and global scales.

4

The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise

75%

Kocot K.

International Journal of Occupational Medicine and Environmental Health

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2020

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vol. 33

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issue 5

649-660

EN

ObjectivesAmbient air pollution is related to adverse respiratory effects. Because of a popular habit of recreational physical activity, the effects of exposure to increased levels of air pollution attract increasing attention. It remains unclear whether the allergy status has an impact on acute responses to air pollution exposure during brief exercise in young adults. The aim of the study was to determine if acute respiratory responses to ambient air pollution during physical exercise differ between young subjects with and without a history of upper respiratory allergy.Material and MethodsOverall, 41 young males with (N = 15, 36.6%) and without allergy (N = 26, 63.4%) performed short moderate-intensive cycle-ergometer sessions in winter air pollution exposure conditions. Associations were analyzed between environmental conditions and acute physiological changes in spirometry, fractioned exhaled nitric oxide (FeNO) levels, blood pressure and pulse oximetry.ResultsNo associations between air pollution concentrations and changes in forced vital capacity, forced expiratory volume in 1 s and the Tiffeneau index were found. In the subjects without allergy, the increased air pollution concentrations recorded during exercise were associated with a post-exercise increase/a smaller decrease in FeNO (SO2: Spearman’s ρ = 0.44, NOx: ρ = 0.51, and particulate matter [PM] levels – PM10: ρ = 0.51, PM2.5: ρ = 0.52). This effect was not observed in the subjects with allergy.ConclusionsUpper-respiratory allergy may be a modifying factor in human response to air pollution during exercise. Exposure to air pollution during brief moderate-intensive exercise did not have any acute negative impact on respiratory and cardiovascular function in young males. However, in the case of FeNO, subclinical post-exercise changes related to air pollution were observed in volunteers without allergy.

5

The influence of Finnish sauna treatments on the concentrations of nitric oxide, 3-nitrotyrosine and selected markers of oxidative status in training and non-training men

75%

Gryka D., Pilch W., Czerwińska-Ledwig O., Piotrowska A., Klocek E., Bukova A.

International Journal of Occupational Medicine and Environmental Health

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2020

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vol. 33

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issue 2

173-185

EN

ObjectivesThe aim of the study was to evaluate the effects of repeated Finnish sauna baths on the concentrations of nitric oxide metabolites (NOx) and 3-nitrotyrosine in relation to pro-oxidative and antioxidative status in young males with different physical activity levels.Material and MethodsThe study was performed on healthy males (aged 20–25 years), representing the training (T, N = 10) and non-training groups (NT, N = 10). The protocol included a series of 10 sauna baths during 3 weeks. One bath consisted of three 15-min sessions, with 2 min recovery. Before the first and the 10th treatment, measurements of body composition, blood pressure, rectal temperature, and plasma concentrations of the total pro-oxidative and antioxidative status, 3-nitrotyrosine and NOx were performed.ResultsA significant increase in physiological parameters during sauna treatments, as well as a significant decrease in the total antioxidative status before the 10th bath, were observed in both groups. The series of sauna baths caused a significant increase in the total antioxidative status in the T group, and a decrease in the total oxidative status in the NT group. A significant decrease in 3-nitrotyrosine in both groups before the last treatment, and also in the T group after the last treatment, was noted. In both groups, a significant increase in NOx concentrations was observed after the first bath.ConclusionsA series of sauna baths contributes to the improvement in the prooxidative/antioxidative balance. The increased production of nitric oxide may lead to a better vascular relaxation and blood flow.

6

DOES THE SUPPLEMENTATION OF ARGININE STAND FOR THE EFFECTIVE METHOD OF IMPROVING THE FUNCTIONAL CAPACITY IN SPORT ACTIVITIES?

75%

Durkalec-Michalski K., Jeszka J.

Studia Periegetica

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2011

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vol. 6

101-110

EN

Arginine is a semi-essential amino acid taking part in the processes involved in the biosynthesis of proteins, the regulation of endothelium activity and the detoxification of an organism. The importance of the proper use of arginine increases in such physiological conditions as a disease, an injury or a substantial overload of an organism. The potential ergogenic influence of arginine supply, through the stimulation of nitric oxide synthesis, human growth hormone and creatine, makes arginine very popular among sportsmen. Many clinical tests present the relationship between arginine supply and the functional capacity improvement and the beneficial regulation of endocrinologic parameters. Such results are explicit while testing convalescents or those suffering from cardiovascular diseases. However, the results of highly-trained and healthy sportsmen are ambiguous. It might be very often observed that there is no connection between arginine and power, strength and muscle mass, the maximum oxygen consumption, the human growth hormone and nitric oxide concentration. Taking it into consideration, the necessity of further research on the functionality of increasing arginine supply among various sportsmen, is firmly supported. Nevertheless, such research needs to be restricted by appropriate procedures, considering cross-over study with double- blind test.

7

Tlenek azotu – podstawowe pytania i odpowiedzi dotyczące roli tej cząsteczki w regulacji wzrostu i rozwoju roślin

63%

Andrzejczak O., Gniazdowska A.

Edukacja Biologiczna i Środowiskowa

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2014

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issue 4

3-10

PL

Tlenek azotu (NO) to bezwonny i bezbarwny gaz powstający jako produkt industrialnej działalności człowieka. W przeszłości, postrzegany był przede wszystkim jako związek toksyczny. Od lat 80. XX wieku datuje się jednak „triumfalny pochód” NO jako cząsteczki sygnałowej, pełniącej bardzo ważne, regulatorowe funkcje w organizmie zwierząt i roślin. Mimo szeroko zakrojonych badań, prowadzonych w ostatnich trzech dekadach, poświęconych roli i metabolizmowi NO w komórkach organizmów fotosyntetyzujących nadal wiele pytań pozostaje bez odpowiedzi. Dotyczą one głównie regulacji stężenia NO w komórkach, szlaków biosyntezy i transdukcji sygnału oraz współdziałania NO z innymi cząsteczkami sygnałowymi, klasycznymi hormonami lub regulatorami wzrostu. Praca stanowi krótki przegląd najnowszej wiedzy na temat funkcji jaką pełni NO w roślinach, ze szczególnym uwzględnieniem znaczenia tej cząsteczki w regulacji wzrostu korzenia.

EN

Nitric oxide (NO) is a small gaseous molecule, occurring in the atmosphere as a product of human industrial activity. In the past, NO was considered mainly as a toxin. In last century there is an increasing amount of data pointing on regulatory role of NO in physiological processes occurring in animals and plants. Although, investigations on NO action in plant cells are carried on in many laboratories all over the world, there are still basic questions to be answered referring to: intracellular NO biosynthesis, perception and signal transduction. Interaction of NO with classical phytohormones and plant growth regulators are of main interest of plant physiologists. The paper presents recent news on NO metabolism in plants, and summarizes the role of NO as a signaling molecule involved in regulation of root growth.

8

Rola argininy w organizmie człowieka

63%

Zdrojewicz Z., Winiarski J., Popowicz E., Szyca M.

Zeszyty Naukowe Państwowej Wyższej Szkoły Zawodowej im. Witelona w Legnicy

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2019

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issue 1(30)

PL

Celem niniejszego opracowania jest przedstawienie roli argininy w organizmie człowieka. Arginina jest aminokwasem względnie egzogennym, co oznacza, że pomimo tego, iż jest produkowana w ludzkim ciele, to dostarczanie jej wraz z pożywieniem jest równie ważne dla zachowania homeostazy organizmu. Główne źródło argininy w diecie stanowią mięso i owoce morza. Aminokwas ten jest syntezowany w czasie cyklu mocznikowego w wątrobie, a także w nerkach. Bierze udział między innymi w wytwarzaniu tlenku azotu, który jest czynnikiem rozszerzającym naczynia. Liczne prace wskazują również na skuteczność suplementacji argininą w zaburzeniach erekcji. Udział argininy w tej reakcji przyczynił się do zainteresowania wielu badaczy. Dowiedziono, że oprócz powszechnie znanego zastosowania argininy jako leku wspomagającego wątrobę w usuwaniu z organizmu amoniaku, odpowiednia suplementacja tego aminokwasu ma pozytywny wpływ na poprawę wartości ciśnienia tętniczego indukowanego ciążą, nadciśnienia płucnego oraz wyrównanie niewydolności nerek, cukrzycy, jaskry, gojenia się ran i profilaktykę udarów mózgu. Uważa się, że stężenie argininy wpływa na rozwój chorób neurodegeneracyjnych postępujących z wiekiem. Aminokwas ten jest też środkiem chętnie stosowanym przez sportowców w celu poprawienia wydolności organizmu. Jednak przeprowadzone do tej pory badania nie potwierdzają jego pozytywnego wpływu w tym zakresie.

EN

The aim of this study is to show the role of arginine in the human body. Arginine is a relatively exogenous amino acid, which means that, although it is produced in the hu- Zygmunt Zdrojewicz, Jacek Winiarski, Ewa Popowicz, Marta Szyca… 171 man body, supplying it with food is equally important for maintaining homeostasis of the body. The main source of arginine in the diet is meat and seafood. This amino acid is synthesized during the urea cycle in the liver as well as in the kidneys. It is involved, among other processes, in the production of nitric oxide, which is a vasodilator. Numerous studies also indicate the efficacy of arginine supplementation in erectile dysfunction. The contribution of arginine in this reaction has generated interest from many researchers. It has been proven that in addition to the well-known use of arginine as a drug contributing to the removal of ammonia from the body, adequate supplementation of this amino acid has a positive effect on the improvement of pregnancy-induced hypertension, pulmonary hypertension, chronic renal failure, diabetes, glaucoma, wound healing and stroke prevention. It is believed that the concentration of arginine affects the development of neurodegenerative diseases progressing with age. This amino acid is also willingly used by athletes to improve the efficiency of the body. However, the studies carried out so far do not confirm its positive impact in this respect

9

Poliaminy – być albo nie być dla rośliny

51%

Ciąćka K., Krasuska U.

Edukacja Biologiczna i Środowiskowa

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2014

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issue 2

3-10

PL

Putrescyna (Put), spermidyna (Spd) oraz spermina (Spm) należą do klasycznych poliamin (PA), występujących u wszystkich żywych organizmów. W przypadku roślin związki te znane są przede wszystkim z dobroczynnej roli, którą odgrywają podczas stresów biotycznych i abiotycznych, jednak pełnią również szereg innych ważnych funkcji, umożliwiających prawidłowe funkcjonowanie komórek. Oprócz bezpośredniego wpływu na procesy życiowe komórki, coraz liczniejsze badania wskazują na współdziałanie PA z cząsteczkami sygnałowymi takimi jak nadtlenek wodoru (H2O2) i tlenek azotu (NO) w ścieżkach transdukcji sygnałów. Zarówno nadmiar jak i brak PA negatywnie wpływa na losy komórki, stąd też istotna jest regulacja biosyntezy i degradacji PA warunkująca ich równowagę. Niniejsza praca stanowi przegląd wiadomości na temat PA i ich oddziaływania na życie roślin.

EN

Putrescine (Put), spermidine (Spd) and spermine (Spm) are basic polyamines (PAs), occurring in every one living organism including plants. Polyamines belong to the group of plant growth regulators and are well recognized due to their protecting role during plant response to biotic and abiotic stresses. PAs play also a crucial role in regulation of many physiological processes e.g. seed germination or plant senescence. Both, excess and deficit of PAs is deleterious for cells. Therefore, control of PAs biosynthesis and degradation determining their homeostasis is of high importance. PAs synthesis is link to pathways of ethylene and nitric oxide (NO) biosynthesis, while PAs catabolism leads to hydrogen peroxide (H2O2) production, thus it is clear that PAs operate in a network with classical phytohormones and signaling molecules. The work summarizes the current knowledge on PAs metabolism and their impact on growth and development of plants.

Refine search results

Clinical and videocapillaroscopic features and serum concentration of nitric oxide in patients with Raynaud’s phenomenon after Multiwave Locked System laser therapy

Receiver operating characteristic analysis of the FeNO biomarker in the diagnosis of asthma

The influence of atmospheric circulation on the air pollution concentration and temperature inversion in Sosnowiec. Case study

The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise

The influence of Finnish sauna treatments on the concentrations of nitric oxide, 3-nitrotyrosine and selected markers of oxidative status in training and non-training men

DOES THE SUPPLEMENTATION OF ARGININE STAND FOR THE EFFECTIVE METHOD OF IMPROVING THE FUNCTIONAL CAPACITY IN SPORT ACTIVITIES?

Tlenek azotu – podstawowe pytania i odpowiedzi dotyczące roli tej cząsteczki w regulacji wzrostu i rozwoju roślin

Rola argininy w organizmie człowieka

Poliaminy – być albo nie być dla rośliny