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Central Portuguese Doctors’ agreement with the “Ten Commandments for patient-centred treatment”

100%
Santiago L. M., Marques P. P., Simões J. A.
Family Medicine & Primary Care Review
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2019
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issue 1
47-52
EN
To ascertain the level of agreement with the “Ten Commandments for patient-centred treatment” by physicians in Central Portugal, exploring differences by age group, sex and medical speciality. Material and methods. An online questionnaire in September of 2016, sent to doctors registered in the Central Regional Section of the Portuguese Medical Association, with weekly reminders to non-respondents. The English wording was translated to Portuguese, a questionnaire with a four-grade answer was created and its reliability determined. Variables such as sex, age group and medical specialty were considered. Descriptive and inferential statistics were performed. Results. A representative yet convenient sample of 811 doctors participated. Their description is as follows: ≤ 35 years n = 203, ≥ 36 and ≤ 55 years n = 217 and ≥ 56 years n = 373, women n = 391 (49.2%), General Practice/Family Medicine (GP/FM) n = 301, medical specialty n = 303 and medico-surgical specialty n = 173. By medical specialty, for commandment 1, there is higher prevalence of “Disagree/Completely Disagree” in the GP/FM specialty (p < 0.001). By gender, for commandment 1, women vs men doctors “Disagree/Completely Disagree” proportion of 11.7% vs 6,4% (p = 0.003). For the younger age groups, there is a greater proportion of “Disagree/Completely Disagree” for Commandment 1 (p = 0.016), for Commandment 4 (p = 0.007), for Commandment 6 (p = 0.001), for Commandment 7 (p = 0.001) and for Commandment 8 (p = 0.020). Conclusions. There is vast agreement with the “Ten Commandments for patient-centred treatment” in central Portugal. For Commandments 1, 3 and 6, the proportion of “Disagree/Completely Disagree” is higher than for the remaining. There is a need for future investigations to explain the present results.
2
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Scientific institutions employing the highest cited researchers publishing in the field of pharmacology/pharmacy and physiology

75%
Pilc A., Buczko W.
Nauka
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2022
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issue 3
3
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Cardiogenic shock induced by a high dose of intravenous morphine

75%
Sein Anand Ł., Korolkiewicz P. K., Sein Anand J.
International Journal of Occupational Medicine and Environmental Health
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2021
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vol. 34
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issue 1
133-138
EN
Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock, and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors’ knowledge, this is the second case of a morphine-related CS reported in literature.
4
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„Magiczna moc pigułki”, czyli o farmakologizacji seniorów

63%
Zbyrad T.
Studia Socialia Cracoviensia
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2018
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vol. 10
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issue 1
EN
“The magic power of the pill”, about the pharmacology of seniors. The article is to look at the risks that pharmacology has. The group is also exposed to seniors, who are especially looking for ways to improve not only the body, but also the vitality that prolongs the youth. The seniors have the ability to decide whether to keep the product on the pharmaceutical market. On the other hand, there is a danger of self-healing due to advertising and geriatric deficiency. The article focuses on the problems generated by the advertising of pharmacological life-support.
5
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Produkty lecznicze i preparaty niewiadomego pochodzenia stosowane nielegalnie jako preparaty poronne

63%
Mazurek A., Baran P., Błażewicz A., Januszewicz P., Jop K., Maurin J.
Medical Review
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2012
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issue 2
238–244
PL
Praca zawiera omówienie wyników opinii kryminalistycznych wykonanych w Narodowym Instytucie Leków w latach 2007–2011 dotyczących preparatów w postaci tabletek i kapsułek, zatrzymanych przez policję i prokuraturę w związku z nielegalnym przerywaniem ciąży. Analizę jakościową tych produktów wykonywano metodami instrumentalnymi. Preparaty zawierały następujące substancje czynne: mizoprostol (Cytotec, Misoprostol 200 μg), mizoprostol i diklofenak (Arthrotec), mifepriston (Mifepristone Tablets 200 mg), prednizon (Encorton). Przedmiotem badań były również kapsułki z omeprazolem. Przy określaniu składu jakościowego masy tabletkowej – zidentyfikowano celulozę mikrokrystaliczną oraz cukry: laktozę i sacharozę. Preparaty z mizoprostolem, czy omeprazolem stosowane są w leczeniu stanów zapalnych żołądka i dwunastnicy, zaś z mizoprostolem i diklofenakiem w leczeniu stanów zapalnych i zwyrodnieniowych stawów. Wykorzystywanie tych produktów leczniczych do usuwania ciąży jest w Polsce nielegalne, a ich działanie opiera się na występowaniu niepożądanych skutków ubocznych występujących niekiedy w trakcie legalnej terapii. Preparat Encorton zawierający substancję czynną prednizon nie wywołuje poronień, lecz jego stosowanie przez kobiety w ciąży może narazić noworodka na niewydolność nadnerczy. Przy wykonywaniu niektórych opinii stwierdzono, że preparaty oferowane na nielegalnym rynku składają się z czystej laktozy i nie zawierają żadnych substancji czynnych.
EN
The paper comprises the discussion of forensic studies results obtained in National Medicines Institute in 2007–2011 period of preparations in a form of tablets and capsules secured by the police and prosecution in connection with illegal abortions. The literature overview on legal an illegal medical abortion in Poland and selected countries in the world has been supplied. A qualitative analysis of these products was performed by means of instrumental methods. Preparations contained the following active ingredients: misoprostol (Cytotec, Misoprostol 200 μg), misoprostol and diklofenac (Arthrotec), mifepristone (Mifepristone Tablets 200 mg), prednisone (Encorton), acetylsalicic acid, methotrexate. Also capsules with omeprazole were studied. Preparations with misoprostol or omeprazole are used in stomach and duodenum inflammatory conditions whereas those with misoprostol and diclofenac in joints inflammatory and degradation conditions treatment. The use of such medicinal products for abortion is in Poland illegal and their action is based on undesirable side effects reported for upper mentioned therapies. Encorton containing prednisone does not cause miscarriages but its use during pregnancy can be involved in infants’ adrenal gland deficiencies. During some experts reports preparations it was found that the preparations offered on the market consist of pure lactose and do not contain any active ingredient.
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