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EN
Introduction and aim. Arterial stiffness (AS) has been associated with reduced cardiorespiratory fitness (CRF). The aim of this study was to verify if there is a relationship between augmentations index (AIx), as an index for AS assessment, and CRF in individuals with type 2 Diabetes Mellitus (T2DM). Material and methods. Observational cross-sectional study including 32 individuals diagnosed with T2DM who performed two evaluations: 1. Arterial stiffness assessment using SphygmoCor and 2. CRF throughout a cardiopulmonary exercise test on a treadmill ergometer. Oxycon Mobile® device was used to obtain oxygen uptake consumption at peak (V˙O2peak); oxygen uptake efficiency slope (OUES) determined by linear regression in reason of the logarithmic transformation of the ventilation and V˙O2 obtained every minute of exercise test. Statistical analysis comprised Pearson’s Correlation and linear regression analysis performed in SigmaPlot. Results. There was a significant correlation between AS and CRF: AIx and OUES; AIx@75 and; OUES. In linear regression, AIx was determinant for V˙O2peak and OUES – AIx and; AIx@75 and V˙O2peak. Conclusion. AS was associated with CRF in individuals with T2DM. These results contribute to the body of evidence linking arterial functional properties to CRF and suggests greater attention for this important index.
EN
Purpose: A study was conducted to investigate the Turkish Validity and Reliability of the Insulin Initiation Attitudes Scale of individuals with Type 2 diabetes. Materials and methods: This methodologically planned study was conducted with 128 Type 2 diabetes mellitus patients who met the sampling criteria. Data collected using a personal information form to identify individuals diagnosed with diabetes and CH-ASIQ, which assessed their attitudes towards diabetes, and the form Insulin Therapy Attitude Scale parallel as a parallel form. For the statistical analysis of the data, Construct Validity, Exploratory Factor Analysis, and Kaiser-Meyer-Olkin test, Confirmatory Factor Analysis, Pearson, Gutmann, Split Half, Spearman, Cronbach Alpha coefficient methods were used. Results: It was statistically significant; it is seen that 14.1% of the participants were in the 41-50 age range, 37.5% were in the 51-60 age range, and 48.8% were 61 and over. According to Kaiser-Meyer-Olkin test, the result was found to be 0.626. According to the results of factor analysis, 4 factors have emerged which have Eigenvalues above 1 and explain 69.48% of the total variance. According to Confirmatory Factor Analysis, Structural Equation Modeling Results of the scale were found to be p=0.000. According to Cronbach Alpha result 0.756. Conclusion: There was a relationship between attitudes to having information about the treatment of diabetics and attitude, and there was the relationship between them. Effects of fear, pain on these findings were observed. The importance of education for a positive attitude was determined. The importance of patients' attitudes towards insulin therapy should be emphasized for adaptation to the disease.
PL
Wstęp. Wzrastająca zapadalność na cukrzycę wśród społeczeństwa stanowi niezwykle istotny problem. Cukrzyca powoduje szereg powikłań, negatywnie wpływających na jakość życia pacjentów. Głównym sposobem leczenia cukrzycy typu 2, oprócz farmakoterapii, jest odpowiedni styl życia. Edukacja zdrowotna ma na celu uświadomienie pacjentom istoty stosowania określonych zachowań prozdrowotnych oraz kształtowania odpowiedniego stylu życia i postaw mających pozytywny wpływ na zdrowie.
EN
Background. The increasing incidence of diabetes among the general public, is a global problem. Diabetes causes a number of complications, adversely affecting the quality of life of the patients. The main method of treating type 2 diabetes in addition to pharmacotherapy, is a good lifestyle, having a positive impact on health. The purpose of health education is to make the patients realize the point of applying to certain health behaviors and the development of appropriate lifestyle and attitudes having a positive impact on health.
EN
The aim of this study was to assess the course of the healing process following the use of dibutyrylchitin (DBC) dressing, a fully degradable material used in the treatment of ulcers which occur during chronic venous insufficiency common in patients suffering from type 2 diabetes. These diseases have a significant impact on the patients’ standard of living, including the potential employment, and on the declining attendance at the current workplace. The implementation of this innovative therapeutic solution may positively affect the above-mentioned difficulties. An analysis of the healing process, following the application of the DBC dressing, was performed. Once the dressing was positioned on the wound, the analysis indicated that it underwent a process of degradation facilitated by the enzymes occurring naturally in the wound. When fully degraded, a further layer was applied. This process was repeated until the wound was fully healed. The study group consisted of 4 patients previously diagnosed with type 2 diabetes. During the observation period, the ulcers in all 4 cases had healed. The examined wound dressings adhered well to the wound surface and degraded within it. No side effects or adverse effects of the applied innovative therapy were observed. An addition of the biodegradable DBC dressing to the standard therapy procedure of ulcers occurring during chronic venous insufficiency among patients with type 2 diabetes indicate safe and effective treatment, which may have a direct reflection in the patient’s professional capacity enhancement. It resulted in the complete healing of all ulcers in each of the observed cases.
EN
The recently observed increase in the incidence of type 2 diabetes and the high percentage of deaths due to its complications, including diseases of the cardiovascular system, is a significant public health problem today. Type 2 diabetes and cardiovascular disease are the leading causes of hospitalisation in highly developed countries. Prevention of metabolic and vascular complications of type 2 diabetes is a priority action according to the recommendations of modern diabetology. Until recently, outpatient diabetes treatment focused solely on metformin, acarbose, sulfonylureas or thiazolidinediones. The appearance on the market of new oral hypoglycemic drugs made it possible to avoid insulin therapy or postpone the stage at which insulin becomes necessary for the control of diabetes. Some of these drugs significantly reduce the risk of death from cardiovascular causes as well as the frequency of hospitalization due to heart failure with a reduced ejection fraction in both people diagnosed with type 2 diabetes and without concomitant diabetes. The drug that permanently connected diabetes and cardiology is empagliflozin – a competitive inhibitor of the sodium-glucose co-transporter 2.
EN
Vitamin D (calcitriol) plays a significant role in many processes. Obtained from diet or synthesized in the skin under UV radiation, it is used not only in calcium homeostasis, but also beneficially affects systems such as the muscoskeletal, immune, and cardiovascular. In recent years, a lot of research have been done regarding the influence of Vitamin D on the human organism and, more importantly, it has been revealed that Vitamin D deficiency is the most common avitaminosis. It is assumed, that about one million people have Vitamin D deficiency globally. Calcitriol deficit is manifested in children by abnormal bone mass and impaired bone mineralization, leading to numerous deformities of the skeleton and in adults by osteopenia. It has been observed that the risk of cancers such as breast, ovarian, prostate, lung, esophagus and pancreas increases proportionally depending on the distance from the equator, as reduced exposure to sunlight limits the ability to produce this vitamin. Studies show a clear dependence of vitamin D deficiency and increased risk of diseases such as type 2 diabetes, cardiovascular diseases, frequent infections of the upper respiratory tract, cognitive disorders, mental disorders, allergies and autoimmune diseases. Studies show that the appropriate dose and timing of supplementation with vitamin D has a clear beneficial effect on health. Determination of blood 25(OH)D is the best method to measure the level of vitamin, and the test is publicly available. To improve the health of the population it is important to raise public awareness about the risks associated with vitamin D deficiency and the possibility of easily accessible supplementation, as well as disseminating information to medical personnel.
PL
Witamina D3 (kalcytriol) pełni wiele ważnych funkcji w organizmie. Pozyskiwana z diety lub syntetyzowana w skórze pod wpływem promieni ultrafioletowych bierze udział nie tylko w utrzymaniu gospodarki wapniowo-fosforanowej, ale także korzystnie wpływa na układ kostno-mięśniowy, układ immunologiczny i układ sercowo-naczyniowy. W ostatnich latach podjęto znaczną liczbę badań dotyczących wpływu witaminy D na ludzki organizm, i co najważniejsze, wykazano, że niedobory tej witaminy są najpowszechniejszą awitaminozą. Niedobór witaminy D szacuje się u blisko miliarda ludzi na świecie. Konsekwencje deficytu kalcytriolu dotyczą już dzieci i objawiają się nieprawidłową masą kostną i zaburzeniami mineralizacji kości, prowadząc do licznych deformacji szkieletu. U dorosłych rozwija się osteopenia. Zaobserwowano, że ryzyko chorób nowotworowych, takich jak rak piersi, jajników, prostaty, płuc, przełyku i trzustki zwiększa się proporcjonalnie w zależności od odległości względem równika, im dalej, tym malejąca ekspozycja na światło słoneczne i tym samym ograniczona zdolność produkcji witaminy. Badania pokazują wyraźną zależność niedoboru witaminy D i zwiększonego ryzyka chorób, takich jak cukrzyca typu 2, choroby układu sercowo-naczyniowego, częste infekcje górnych dróg oddechowych, zaburzenia poznawcze, zaburzenia psychiczne, alergie oraz schorzenia autoimmunologiczne Badania wykazują, że odpowiednia dawka i czas suplementacji witaminą D, ma korzystny wpływ na stan zdrowia człowieka. Oznaczenie we krwi 25(OH)D jest najlepszą metodą do sprawdzenia poziomu witaminy, a badanie jest ogólnie dostępne. Zwiększenie świadomości społeczeństwa odnośnie ryzyka związanego z niedoborami witaminy D oraz badań i możliwości łatwo dostępnej suplementacji, a także rozpowszechnianie informacji wśród personelu medycznego, są warunkiem poprawy stanu zdrowia całej populacji.
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