Full-text resources of CEJSH and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Results found: 5

first rewind previous Page / 1 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
EN
In 2018 we celebrate the 250th anniversary of the Jędrzej Śniadecki’s birth. This work aims to show the importance of his thoughts for the development of natural sciences. He studied at some of the largest universities in Europe, where he met great scientists of the Enlightenment. The effects can be seen in his works. He was remembered as a founder of Polish biochemistry, anthropology and pathology, also as the author of chemical terminology and  language. The essence of his thoughts is Theory of organic being, which is an attempt to answer the question: „what is life?”. Jędrzej Śniadecki introduced a new definition of life based on the term „organic power”. This work shows how import are the thoughts of Jędrzej Śniadecki in the context of the times in which he lived, as well as the following development of natural sciences, what makes him and his theories worth memory.
2
Publication available in full text mode
Content available

Regulatory RNAs in the brain

100%
EN
Nervous system is characterized by its uniqueness in cells origin, their variability, electrical properties of the nervous cell membrane, response to external signals, neuronal network and changes in synapses activity that are the basis of higher brain functions, such as learning and memory. Brain is a superior organ of human body with an extremely efficient regulation system. Apart from protein and small-molecule regulators, ribonucleic acids (RNAs), especially noncoding proteins (ncRNAs), play a crucial controlling role in the brain. They are present in every cell, from bacteria to primates and have regulatory, catalytic as well as structural function. Many specific ncRNAs have been identified in human brain, responsible for development and functioning. Disturbances in ncRNA synthesis and mechanism of action are connected to diseases such as autism, schizophrenia, Alzheimer disease, Prader-Willi syndrome and others.
PL
Deoxyribonucleic acid (DNA) was identified 140 years ago by a Swiss physician Friedrich Miescher. His discovery was fundamental for the development of biochemistry, genetics and molecular biology. Contemporary biology, biotechnology and medicine largely depends on our ability to analyze, synthesize and manipulate DNA. We present highlights of the history of DNA research from the very beginning to the sequencing of human genome.
EN
This year we are celebrating 150 anniversary of the discovery of DNA by Friedrich Miescher. His finding initiated a series of discoveries that allowed to depicts life's most famous molecule with novel features with considerable biological interest. In this article we recall the biggest mile stones of 150-year history of DNA and present the context and meaning of several key observations that have brought us closer to understanding DNA. 150 years ago, people had no idea that DNA existed, and they certainly hadn’t heard of DNA structure and sequencing. We now know that DNA is a dynamic, tortuous coil, constantly shuffling and unwinding. Today DNA is all around us, in a physical sense and in a cultural sense. It is really part of our culture. We will discuss also the little known facts, often overlooked in similar discussions. We will focus particularly on Professor Richard Altmann's from Iława, whose contribution to knowledge about nucleic acids is significant, although not well recognized so far.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.