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The role of erythrocyte distribution width in predicting poor outcomes in geriatric patients with acute pancreatitis

100%
Şeyma Akça H., Özkan A.
European Journal of Clinical and Experimental Medicine
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2022
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issue 4
417-422
EN
Introduction and aim. In our study, our aim was to evaluate the relationship between red cell distribution width (RDW) values and prognosis in geriatric patients with acute pancreatitis. Material and methods. Patients over the age of 65 and diagnosed with acute pancreatitis who applied to the Emergency Department of Ümraniye Training and Research Hospital between 16.07.2021 and 15.05.2022 were included in our retrospective study. RDW levels were recorded using the hospital data system. Results. Our study included 184 patients, 19 (10.3%) of which died. Sixty-five percent of our patients were women. The mean hospital stay was 5 days (from 3 to 9). A statistically significant relationship was also observed between high RDW and mortality (p=0.006). The diagnostic test performance analyses of CRP, and RDW in predicting mortality revealed that they were statistically significant in predicting mortality, with the AUC value being calculated as 0.66 (0.6061–0.7368) for CRP, with a cut-off value of 22; and 0.69 (0.6909–0.7368) for RDW, with a cut-off value of 14.5 (p=0.019, p=0.006, respectively). Conclusion. Hematological parameters can help predict a prognosis in patients with acute pancreatitis. Although RDW is not statistically more significant than CRP, it can be used as a prognostic marker in patients with acute pancreatitis.
2
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Effect of the prognostic nutritional index and systemic immuneinflammatory index in predicting short-term mortality in geriatric patients with SARS-CoV-2 infection

71%
Özkan A., Muzaffer İslam M., Şeyma Akça H., Emre Eroğlu S., Aksel G.
European Journal of Clinical and Experimental Medicine
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2022
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issue 4
399-403
EN
Introduction and aim. We aimed to investigate whether systemic immune inflammatory index (SII) and prognostic nutritional index (PNI) were associated with short-term mortality in geriatric patients with SARS-CoV-2.Material and methods. Our study was designed retrospectively. The data of patients that presented to a single center. The primary outcome of the study was the diagnostic value of SII and PNI in predicting 28-day mortality in geriatric patients with SARS-CoV-2 pneumonia. Results. 272 geriatric patients with SARS-CoV-2 included. The median PNI was 42.5, and the median SII was 687.6 (430–1404.2). In univariant analysis, PNI and SII has a significant relationship with mortality (p<0.001 and p=0.008, Mann-Whitney U test). PNI had an area under the curve (AUC) value of 0.680, which was significantly higher than that of SII (AUC: 0.6). The odds ratio of PNI (>40.1) and SII (<1.267) for 30-day mortality were determined as 1.12 , and 1. Conclusion. In conclusion, the blood tests used to calculate PNI and SII are routinely included in complete blood count and biochemistry tests that can be performed in every hospital. According to the results of the current study, the mortality group had significantly higher SII values and significantly lower.
3
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The role of the hematological inflammatory index and systemic immuno-inflammation index in acute cholecystitis

61%
Özdemir S., Altunok İ., Özkan A., Muzaffer İslam M., Algın A., Emre Eroğlu S., Aksel G.
European Journal of Clinical and Experimental Medicine
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2022
|
issue 3
330-335
EN
Introduction and aim. Acute cholecystitis is one of the most common hepatobiliary emergencies. We aimed to investigate the role of the initial hematological inflammatory index and systemic immuno-inflammation index in predicting short-term mortality in patients with acute cholecystitis. Material and methods. This study with a retrospective observational design was conducted at the emergency department of a tertiary teaching hospital. Patients admitted to our clinic between June 15, 2021, and March 15, 2022, according to the Tokyo criteria were included in the sample. The hematological inflammatory index and systemic immuno-inflammation index were calculated using the hematological test results of the patients evaluated at the emergency department. Survivor and non-survivor groups were formed according to all-cause 30-day mortality. The differences between survivor and non-survivor groups were investigated. Results. A total of 194 patients were included in the final analysis. The median age of the study population was 59 (25th–75th percentiles: 46.75–72) years. The rate of all cause-short-term mortality was 7.7. There were significant differences between the survivor and non-survivor groups in terms of the neutrophil count and the systemic immuno-inflammation index (p=0.007, 0.034, respectively; Mann-Whitney U test). No significant difference was found in the remaining laboratory parameters (lymphocyte count, platelet count, and hematological inflammatory index) (p=0.220, 0.489, 0.367 respectively; Mann-Whitney U test). Conclusion. The systemic immuno-inflammation index was determined to be significantly higher in the non-survivor group than in the survivor group among the patients with acute cholecystitis. However, there was no significant difference between these two groups in relation to the hematological inflammatory index
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