This paper describes methodological and theoretical problematics in creating knowledge about the relations between politics and biology. eThse problematics are cit ed from philosophy and philosophy of science, critical theory, and scientific method(s). ehT case of politics characterized by the dark tetrad - narcissism, psychopathy, Machi avellianism, and sadism - and biology characterized by evolutionary theories are used as an example. eTh conclusion is that the relations between politics and biology are un knowable and attempts to apply putative knowledge of such relations have led to tragedy and atrocity throughout history.
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