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The history of transplantation in the world and in Poland

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Kobus G., Małyszko J.

Progress in Health Sciences

2015

vol. 5

issue 1

258-264

Transplantation is the most spectacular success of medicine in the XX century. Transplantation became the effective and standard method of treatment of end-stage organ failure. It enable not only improvement of the quality of life, but prolong survival as well. How it was a long history dating back into the ancient times. Development of clinical transplantation was possible owing to the enormous progress in surgical techniques, invention of vascular anastomoses, knowledge of immunological mechanisms underlying tolerance and rejection processes, development of immunosuppressive therapy and multidisciplinary cooperation. We learnt about the new techniques of assessment of HLA matching, preservation of retrieved organs, new immunosuppressive regimens, more efficient antirejection therapy and prophylaxis of complications, mainly infections. The future should bring the further development of clinical transplantation, however we should be aware of new challenges as xenotransplantation, stem cells or tissue cultures or even development of artificial organs cultured in the laboratories using human cells and tissues.

Pseudohyperkalemia: in vitro phenomenon or misdiagnosis. A case report

61%

Struniawski K., Pogorzelski S., Wróblewski D., Kuźma Ł., Kobus G., Dobrzycki S.

Progress in Health Sciences

2018

vol. 8(2)

239-242

Introduction: Hyperkalemia is a common electrolyte disturbance that occurs within many patients. The more often prevalence of cardiovascular or renal diseases is, the more frequent medical issue hyperkalemia will be. An increasing quantity of entities requires taking medications that affect electrolyte hemostasis. Therefore, reasons for hyperkalemia should be deeply reflected. One of them is pseudohyperkalemia. Purpose: In this study diagnostics and treatment of hypokalemia were presented based on the case report of a 56-year-old man. Case presentation: A 56-year-old man was admitted to the Department of Invasive Cardiology of Medical Hospital of Białystok for complaints of strong chest pain associated with palpitations, cold sweats, feelings of general weakness and anxiety. The patient had no medical history of chronic diseases and neglected to take any medications at length. The laboratory tests performed at admission showed an increased serum concentration of potassium. Through the whole hospitalization, many medications were implicated to overcome hyperkalemia (diuretics, calcium resonium, inhalation with beta2-adrenergic agonists, intravenous infusion of glucose with insulin) with no effect. Hormone test was performed, the results excluded Addison’s or pituitary disease. Differential diagnosis with arterial blood draw showed normal potassium serum concentration. Conclusions: Hyperkalemia is encountered in a broad spectrum of patients. The severely elevated level of potassium could lead to life-threating conditions. Therefore, proper diagnosis making process is a matter of great importance. As clinicians, we need to base not only on laboratory but also examine the whole picture of the patient. Misdiagnosing pseudohyperkalemia might result in unnecessary medical management.

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2 Progress in Health Sciences

2 Kobus G.

1 Dobrzycki S.

1 Kuźma Ł.

1 Małyszko J.

1 Pogorzelski S.

1 Struniawski K.

1 Wróblewski D.

1 2019

1 2015

Search results

The history of transplantation in the world and in Poland

Pseudohyperkalemia: in vitro phenomenon or misdiagnosis. A case report