The aim of this study was to explore the efficacy of brief universal drug use prevention program among university students. The changes (pre-and post-program) in scores of sense of coherence (SOC-13; Antonovsky, 1993), resilience (Notario-Pacheco et al., 2011), and alcohol use (AUDIT, Babor, Higgins-Biddle, Suanders, Monteiro, 2001) were explored (34 program participants, 75 students in control group). A statistically significant increase in comprehensibility and resilience, as well as a significant decrease of alcohol use from baseline to follow up measures were found following participation in the program among students in the experimental group. Findings of this study supported flexibility, a potential for changes in cognitive component of SOC, resilience, and alcohol use among university students who participated in short universal drug use prevention program.
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