Search results - CEJSH

1

Hyalinising clear cell carcinoma of salivary gland: a case report

100%

Michał Osuchowski M., Dorota Bartusik-Aebisher D., Ewa Kaznowska E., David Aebisher D.

European Journal of Clinical and Experimental Medicine

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2020

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issue 2

127-130

EN

Introduction. Clear cell carcinoma, not otherwise specified/hyalinising clear cell carcinoma of the salivary gland (HCCC) is a malignancy that arises in minor salivary glands. It rarely leads to distant metastases or cancer-related death but has the potential for recurrence and focal metastases. Aim. A case is reported. Description of the case. A 72 years old female patient has reported to the Clinic of Otolaryngology with a tongue lesion. The patient had no history of malignancy. The lymph node has been surgically removed for further examination. Cords and nests of clear cells and cells with eosinophilic cytoplasm in a hyalinized stroma were identified within the lymph node. After the diagnosis the patient has been transferred to another Oncology Hospital for further treatment. Conclusion. The diagnosis of clear cell carcinoma may be challenging because many of it‘s features frequently overlap with other salivary gland lesions.

2

Choroba nowotworowa – w obliczu zagrożenia życia

100%

Paul-Kańska J., Wydział Organizacji i Zarządzania Politechniki Łódzkiej

Acta Universitatis Lodziensis. Folia Psychologica

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2007

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vol. 11

EN

The article presents a multi – dimensional look at the issue of coping with stress, situating health monitoring and the sense of self – effectiveness in people with recognized cancer. The results of self – studies were displayed, showing whether and to what degree the strategies of managing the disease depend on the subjects’ sex. The existence of the relationship between the tested variables (situating health monitoring and the sense of self – effectiveness) and the strategies of coping with the disease stress, was proved.

3

Satisfaction with nursing care provided to patients who have undergone surgery for neoplastic disease

80%

Gorari A., Theodosopoulou E.

Progress in Health Sciences

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2015

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vol. 5

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issue 1

29-41

EN

Purpose: To investigate satisfaction of cancer patients, who have undergone cancer surgery, with nursing care and the association of patient satisfaction with demographic and clinical characteristics. Materials and methods: The study population consisted of 181 patients with cancer who have undergone surgery and were hospitalized in clinics of University General Hospital of Greece. The instrument used in the study was the «Measurement of patient satisfaction scale» (MPSS). The model of multiple linear regression was used with the method of backward stepwise linear regression. Results: The results of the study showed that patients were overall satisfied with nursing care. The areas they were less satisfied were «Resting time», «Information», «Education», «Personal preferences» and «opportunities for participation in care». The patient satisfaction had a statistically significant association with the following characteristics of the patients: (a) patient education, less educated patients showed higher levels of satisfaction (p<0.001) and (b) the hospitalization at the chemotherapy clinic, patients hospitalized at chemotherapy clinic showed higher levels of satisfaction than patients hospitalized in the other two clinics (p=0.002). Also, there was a statistically significant association between the patients education level and the item «I wish nurses have knowledge about alternative methods of dealing with some disease symptoms» (r=-0.22, p=0.003). Conclusions: The training of the nursing staff that work in clinics where patients with cancer are hospitalized, is necessary not only at a scientific level but also at a communication level. The satisfaction of surgical patients with cancer should be continually evaluated in order to assess patients’ needs, to improve poor or problematic aspects of care and to manage patients’ personalized and expressed needs.

4

Assessment of knowledge about obesity among students in a medical college in Kancheepuram district, Tamil Nadu

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Shrivastava S., Shrivastava P., Ramasamy J.

Progress in Health Sciences

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2013

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vol. 3

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issue 1

54-60

EN

Introduction: Overweight and obesity are the fifth leading risk for global deaths. It is not only the degree of excess fat that is important, but also its distribution in the body that determines the health risks associated with the condition. The aim of the study is to assess the knowledge of medical students pertaining to obesity. Methods: A cross-sectional descriptive study was conducted among first-year medical students in March of 2013. A universal sampling method was employed, and all first-year students were included as subjects in the study. The total sample included 138 students. After obtaining informed consent, a pre-tested semi-structured questionnaire was admini-stered to each of the participants. Utmost care was taken to maintain privacy and confidentiality. Statistical analysis was done using SPSS version 17. Frequency distributions and percentages were calculated for all the variables. Results: A lack of physical activity and the presence of stress were identified as the most common risk factors for obesity development. Approximately, 73(52.9%) students were of the incorrect opinion that gynaecoid obesity was more dangerous than android obesity. The most common strategy cited by 107(77.5%) respondents for prevention of obesity was regular exercise. Conclusion: The study revealed that although the majority of the medical students were aware of the risk factors of obesity, many gaps, which need to be bridged, were identified in their knowledge. These medical students could be actively involved in awareness campaigns for delaying the onset of lifestyle diseases.

5

Serum beta-glucuronidase in colon cancer patients dependent on alcohol and nicotine: preliminary report

80%

Waszkiewicz N., Zalewska-Szajda B., Repka B., Szulc A., Kępka A., Chojnowska S., Dadan J., Ładny J., Zwierz K., Szajda S.

Progress in Health Sciences

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2012

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vol. 2

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issue 2

64-69

EN

Introduction: Beta-glucuronidase (GLU) is a lysosomal exoglycosidase involved in the catabolism of glycoconjugates. Excessive GLU activity may be a primary factor in the etiology of colon cancer. The stimulation of glycosidases and other degradative enzyme activity has been noted in cancers as well as in alcohol and nicotine addiction. Purpose: To compare the serum GLU activity between alcohol- and nicotine-dependent colon cancer patients and colon cancer patients without a history of alcohol- and nicotine-dependence. Materials and methods: Material was the serum of 22 colon cancer patients, 11 of whom met alcohol and nicotine dependence criteria. The activity of serum GLU (pKat/ml) was determined by the colorimetric method. Carcinoembryonic antigen (CEA) concentration (ng/ml) in the serum was determined by the immunoenzymatic method. Comparisons between groups were made using the Mann-Whitney “U” test. Spearman’s rank correlation coefficient was used to measure the association between two variables. Results: The activity of serum GLU was significantly higher in colon cancer patients with a history of alcohol and nicotine dependence, than in the colon cancer patients without a history of drinking and smoking (p=0.003). There was no significant difference in the CEA concentration between colon cancer patients with and without a history of drinking and smoking. Conclusion: Alcohol and nicotine addiction may increase the serum GLU activity in all cancer patients, as already seen in colon cancer patients. This may potentially be important for the degradation of pericancerous matrix, tumor growth, invasion and metastasis

6

Sprachliche Krankheitsbilder und emotionale Metaphern bei der Krebserkrankung

80%

Guławska-Gawkowska M.

Linguistische Treffen in Wrocław

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2020

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issue 18

109-135

EN

Of all present diseases, the most cancer is metaphorized. The ancient name for the disease is already a metaphor that provides a certain frightening picture and awakens strong emotions. The brilliant essay “Illness as a metaphor” of Susan Sontag and the popular science book “The Emperor of All Maladies: A Biography of Cancer” of Siddhartha Mukherjee provides a compilation of metaphors that relates not only to cancer but also to their treatment and beyond to doctors, scientists and patients. These metaphors are presented from the linguistic point of view in this article and analyzed in terms of the long metaphor research, which is not the case in the two sources.

7

The incidence of malignant tumor among the adult population of Belarus, undergone to influence of radiation owing to the accident on the Chernobyl atomic power station

80%

Kotava A., Sasnouskaya A.

Progress in Health Sciences

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2011

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vol. 1

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issue 1

14-20

EN

Purpose: We presented results of long-term monitoring of incidence malignant tumor among the adult population of Belarus, according to the Belarus state register of the persons, undergone to influence of radiation owing the accident on the Chernobyl atomic power station. Material and methods: The analysis of primary incidence of malignant tumor among various categories of the population living in Belarus and undergone the influence of ionizing radiation owing to the accident on the Chernobyl atomic power station is lead. The analysis is leading on the directly age-standardized parameters designed with the use of the world standard population. Levels, dynamics and growth rate in comparison with a similar parameters control group were estimated. Those localizations of a cancer which taking into account world experience can be radiation - induced to have been included in research only. Results: The carried out research has revealed of statistically excess of a level and rate of incidence malignant tumors lung, stomach, colon, skin, urinary bladder among various categories of the population of the injured from Chernobyl accident in comparison with the control group. The most expressed distinctions were characteristic of the liquidators. The changes of levels and dynamics of incidence are revealed for organs of the breath, digestion, urinary system, which are the basic ways of receipt and deducing radionuclide’s. Among all observable groups of the adult population the significant excess of incidence by thyroid cancer is revealed. Conclusion: Among the adult population of Belarus should continue to monitor the incidence of malignant tumor, provide an assessment of doses to different groups of affected people, plan and conduct analytical radiation-epidemiological studies.

8

Unique Mastic Resin from Chios

80%

Chadzopulu A., Koukouliata A., Theodosopoulou E., Adraniotis J.

Progress in Health Sciences

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2011

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vol. 1

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issue 1

131-136

EN

Authors presented analysis of the literature on medical use Pistacia lentiscus var. Chia. Mastic tree thrives and gives mastic only in the south part of the island of Chios (Greece) and nowhere else in the Word. Mastic oil has been found to be effective in both preventing and treating various cancers. It heals also pectic ulcers by killing Hellicobacter pylori. Natural mastic gum has also been proven to absorb cholesterol thus diminishing chances of heart attacks and high blood pressure, and helps reduce triglyceride and total lipid levels of the organism.

9

Does anybody support the supporters? Social support in the cancer patient-caregiver dyad

80%

Dębska G., Pasek M., Wojtyna E.

Family Medicine & Primary Care Review

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2017

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issue 2

110-113

10

The knowledge of selected cancer prevention methods among Polish outpatients

80%

Kurczewska-Michalak M., Kardas P.

Family Medicine & Primary Care Review

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2017

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issue 3

235-238

11

Helping a Family with a Person in the Terminal Stage of Cancer Based on the Example of the Good Samaritan Hospice in Lublin

80%

Kalinowski M.

Roczniki Teologiczne

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2018

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vol. 65

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issue 10: Nauki o rodzinie - English Online Version

73-87

EN

The family is the most secure supporting foundation in the situation of a loved one who is suffering and dying. Its activity results from the strength of intra-family bonds and appropriate legal regulations supporting its actions based on the principle of justice and support. Implementing these activates is based on the social capital of activities arising from the principles of the common good, social love and solidarity. An example is the Social Hospice Care Center operating within the Lublin Society of the Friends of the Sick at the Good Samaritan Hospice, which shows the practical applications of the above course of action within family assistance.

12

The effect of the burden of patient care with cancer on family caregivers

80%

Anterrioti C., Alikari V., Kelesi M.

Progress in Health Sciences

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2020

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vol. 10(1)

102-107

EN

Cancer is a major problem that affects today's society. Besides patients suffering from this disease, cancer has also a huge impact on the quality of life of the family. This study aimed to investigate the latest bibliography on the effect of the burden of patient care with cancer on family caregivers. Family caregivers face physical health problems such as physical pain, fatigue, sleep disturbances. Moreover, several psychological effects are shown, in which various disorders such as depression are included. Psychological disorders, also, include adjustment disorder, panic disorder, anxiety, and emotional reactions such as anger, frustration, and fear. In the financial sector, caregivers face several problems due to the coverage of medical needs which are reinforced by reducing or stopping their work because of the care burden. At the same time, they are confronted with social impacts in which loneliness and isolation are attributable to the limitation of their social activities. As far as the age group of the patient is concerned, the effects of caring for young patients are more psychological than physical in opposite to the older people. The burden experienced by the family of the cancer patient exhausts family and it becomes necessary to identify problems and assess their needs. Health professionals should strength caregivers with actions such as psychological support, training, and participation in social and supportive programs in order to improve their personal health and quality of life.

13

Primary healthcare services and patients with neoplastic disease

80%

Papastergiou K., Lavdaniti M.

Progress in Health Sciences

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2016

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vol. 6(2)

109-116

EN

Introduction: The primary health care services holding the central role in the prevention of various diseases. Cancer is the second leading cause of death worldwide. Primary healthcare services, holding a coordinating role in staging, treatment and prognosis of cancer. Purpose: To present the role of primary health care services in primary and secondary prevention of cancer. Materials and methods: A search was made in the PubMed and Scopus databases for reports on primary health care services in cancer patients. Results: Monitoring and early detection are some roles of care. The preventive medicine focuses on health promotion and disease prevention, helping people to enhance their own health. Specifically, majority of researches revealed that mammography ranged 44% to 69%. Also, the screening of cervical cancer by early examination of Pap smear, the percentage ranged 24% to 36%. The screening of prostate specific antigen (PSA) test ranged about 55%. The health professionalsfocused on individual, group and community interventions aimed at health promotion and prevention through programs and counseling. Conclusions: The interest of the fact that the primary care services have multidimensional roles for eliminating the occurrence of cancer. Prevention and health promotion programs, informing the population, campaigns on the part of health professionals for more frequent screening and early diagnosis in general symptoms of cancer, are fundamental principles of these services.

14

Nutrigenomics – a new approach for cancer prevention and treatment

80%

Piątek W., Milewska M., Krasowska U., Terlikowska, K.M

Progress in Health Sciences

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2018

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vol. 8(1)

151-157

EN

Diet is a major environmental factor which maintains metabolic balance and body homeostasis. The aim of the study was to present the latest reports on the biological activity of the food compounds in a critical review. It has been shown that bioactive substances supplied with food e.g. polyphenols, flavonoids or phenolic acids exhibit immunomodulatory and anti-inflammatory fun-ctions. What is more, they favourably downregulate major oncogenes and enhance suppressors’ expression. Studies show that these substances can be an important component of cancer prevention and treatment. However, there are micronutrients like iron or copper which elevated levels in cancer cells occurs and should be considered as a therapeutic targets.

15

Nursing care of a child with acute lymphoblastic leukemia

80%

Ślifirczyk A., Piszcz P., Ślifirczyk M., Michalczuk T., Urbańczuk M., Celiński M., Bytys M., Domańska D., Nikoniuk M.

Progress in Health Sciences

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2018

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vol. 8(2)

168-173

EN

Every year a very large number of children in the world suffer from acute lymphoblastic leukemia, and for years there has been a steady increase in the number of new cases. Acute lymphoblastic leukemia accounts for 75% of leukemia cases in the world. Lymphoblastic leukemia is a cancer disease that originates in B or T cell lymphocytes, which expansion takes place in blood and in the bone marrow. The etiology of the disease is not fully understood because it consists of several factors conditioning its formation. The most important element is the early detection and taking actions resulting in effective disease control through treatment and care of the patient. The nursing process should allow the patient to be involved in and accept the ongoing cancer process, and medical personnel, family and specialists in such fields as psychology and psychiatry should participate.

16

The expression of CD44, CD90 and CD133 in response to cisplatin in hepatocellular cancer cells

80%

Yaprak Donmez Cakıl Y. D., Zeynep Gunes Ozunal Z. G., Damla Gokceoglu Kayalı D. G., Ranan Gulhan Aktas R. G.

European Journal of Clinical and Experimental Medicine

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2021

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issue 1

18-22

EN

Introduction. Cancer is a leading cause of mortality. Hepatocellular cancer is one of the malignancies associated with poor outcome and resistance to pharmacotherapy. Cancer stem cells (CSCs) contribute to resistance to therapy and hence lead to the treatment failure of tumors. Aim. This study aims to explore the expression of CSCs in response to cisplatin treatment in HepG2 hepatocellular cancer cell line. Material and methods. Cell proliferation test, CCK-8, was used to evaluate the cell proliferation following cisplatin treatment for 72 hours. The expressions of CSC markers CD44, CD90, and CD133 were assessed by flow cytometric analysis. Results. The results showed a dose-dependent decrease in cell proliferation and increased expression of CSC markers CD44 and CD90 in response to cisplatin. Conclusion. Understanding the roles of CSC markers may point to new targets and therapeutic strategies to predict and overcome cisplatin resistance.

17

Konsekwencje choroby nowotworowej w rodzinie

80%

Rospęk P.

Studia Pastoralne

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2020

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vol. 16

126-141

EN

Malignant tumor is the second most frequent cause of death in Poland. A steady increase in cancer mortality has been observed in Poland. The introduction of modern research methods has contributed to an increase in cancer detection and enhanced therapeutic effects. New medical achievements, the introduction of new drugs or more optimal treatment techniques can become a source of further improvement of the situation. The appearance of cancer in the family completely changes the lives of its individual members. The way of thinking, feelings, actions, the hierarchy of goals and values change depending on the phase of the disease and the progress of treatment. Nevertheless, the fight against cancer in the family is still an issue little known in Polish psycho-oncology. The article shows the impact of cancer on the patient’s family, focusing on the sociological, psychological and spiritual dimensions of attitudes and reactions of families towards oncologically ill relatives. One of the author’s main goals is to examine how fear and anxiety develop in families affected by cancer.

18

Cancer on the Holodeck: Metaphors and Cultural Construction of a Disease through Digital Games

80%

Navarro-Sierra N., Carrillo-Vera J. A., Gómez-García S.

Acta Ludologica

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2020

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vol. 3

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issue 2

4-20

EN

A study from the OECD published that Cancer is one of the main causes of mortality in developed societies, with remarkably high prevalence, incidence and mortality rates for both sexes. This study closely examines nine digital games to elucidate how they conceptualize a disease like cancer around a narrative concerning the sickness, patients, treatments and outcomes. Discourse and content analysis techniques were applied to the message contained in the games looking to illuminate the connection between the narrative core, the audio-visual representation and the interactive aspects of the game, within the parameters of values-conscious design applied to digital games. This provides some evidence about the cultural and visual aspects of how game designers conceptualize the disease as a part of society. This research uncovers culturally embedded themes and reveals the prevalence of metaphor use in cancer discourse which relied on science, social support and spiritual convictions for social empowerment, building empathy and identification.

19

Clinical application of monoclonal antibodies in targeted therapy

80%

Maciej Superson M., Katarzyna Szmyt (, Katarzyna Szymańska K., Kamil Walczak K., Jeremi Wnorowski J., Łukasz Zarębski Ł.

European Journal of Clinical and Experimental Medicine

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2019

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issue 4

338-346

EN

Introduction. Recently, monoclonal antibodies (mAbs) have become powerful human therapeutics in the diagnosis and treatment of many diseases. Drugs based on mAbs are approved for the treatment of cardiovascular, respiratory, hematology, autoimmunology, and oncology diseases. Aim. To present the current state of knowledge about the application of mAbs in the therapy of various diseases such as cancer, autoimmune and Alzheimer’s diseases. Material and methods. We conducted a thorough review of the scientific literature from the following databases: EBSCO, PubMed, Science Direct, and Springer Link. Results. Currently, the Food and Drug Administration (FDA) has approved more than 50 therapeutic mAbs which are applied in various clinical trials. Action of mAb are based on various mechanisms, including directly targeting the cells, modifying the host response, recognizing and degrading molecules as well as delivering cytotoxic moieties. Conclusion. Despite some limitations including side effects, and therapeutic challenges, monoclonal antibodies are an attractive option for the development of new therapies and molecular drug targets against a wide range of common diseases due to their specificity and flexibility. MAbs are considered as a great hope for medicine, and effective and safe drugs in the treatment of various diseases.y

20

Cancer patients’ attitudes towards holistic complementary and alternative medicine in the management of sleep problems

80%

Baykal D., Dedeoğlu Demir B., Yildirim D.

European Journal of Clinical and Experimental Medicine

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2023

|

issue 3

546-552

EN

Introduction and aim. Sleep problems are frequently experienced in cancer patients and complementary and alternative medicine (CAM) is solve the problem. However, patients’ attitudes towards this practice are crucial. This study was purpose to investigate the attitudes of cancer patients towards CAM practices in the management of sleep problems. Material and methods. This cross-sectional. and descriptive study was conducted between February-June 2020, on 140 cancer patients in oncology/haematology clinics, three different hospitals in Istanbul. Data were collected by using the Information Form, “Richard Campbell Sleep Questionnaire and The Attitudes towards Holistic Complementary and Alternative Medicine scale”. Results. It was found that the patients had problems with sleep in general 42.74±21.31, mostly in the aspect of the quality of sleep 36.28±26.1. It was determined that stage IV cancer, education and income level of patients affect sleep problems. While female holistic health attitudes were more negative and, their attitudes towards CAM were positive. It was found in the analysis of variance that was performed to determine the difference between the mean scores towards sleep problems of patients in different stages (F=3.062; p<0.05). Conclusion. It was found that cancer patients usually had sleep problems, and their attitudes towards CAM practices were positive.

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