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Background. Diseases of the cardiovascular system (CVS) are among the most common diseases of humankind (WHO). Monitoring of blood pressure (BP) is an accessible method for evaluating global hemodynamic processes. The functional reserves of the circulatory system are traditionally determined by the use of functional loading trials and tests. Objectives. The aim of the study is to enhance the information collected during the blood pressure measurement process by studying the levels of adaptation of the CVS to physical activity with morphological, temporal, spectral and correlation analyses of arterial oscillography (AO). Material and methods. In 178 healthy individuals aged 18–20 years, arterial oscillograms were recorded during blood pressure measurement and correlations of the functional reserve of the cardiovascular system at various stages of adaptation to a Ruffier test were investigated. Results. The proposed methods of AO analysis significantly increase the informativeness of the procedure for blood pressure measurement, provide an opportunity to conduct a visual analysis of AOs and to assess the state of the cardiovascular system, its reserve capabilities and its ways of adapting to shoulder compression at rest, after physical load and in the process of recovery. Conclusions. Using the information technologies proposed by the authors of the morphological, temporal, spectral and correlation analysis of arterial oscillograms, their evaluation and clinical interpretation significantly increase the informativeness of the blood pressure measuring process. They can be used for early detection of pre-morbid conditions and functional blood circulation reserves, which will help the physician to more effectively plan a preventative, diagnostic and therapeutic process.
EN
Evidence from research has not only excluded negative consequence of moderate wine consumption, but associated consumption of grapes and their components with a protective impact on health. Wine demonstrates anti-cancer, antioxidant and defensive results for the cardiovascular system. Not surprisingly, there is an interest in exploring a growing consumption of wine and turning it into innovative solutions with different approaches, making use of areas that have undergone significant transformations over last decades as a results of a global dynamical change which offer new consumption patterns seen now as driving forces for stagnating economies of the XXI century. This article builds on this perspective aiming to shed some light on wine consumption patterns, health attitudes and the perception and awareness of positive effect of a moderate consumption of wine on human health. The study was carried out between March and May 2013 as a self-administered questionnaire to visitors of liquor stores, wineries, wineries of the Lower Silesia region, Poland. Results demonstrate an interest in consumption of wine with opposite tendencies in opinions about the recommended about the recommended wine quantity of consumption. Some consciousness of health-related benefits and applications of wine show an increasing awareness in this matter.
EN
Objectives: To investigate the association between per capita pesticide consumption and infant mortality rates from CNS and CVS congenital malformations in microregions in the South and Southeast Region of Brazil. Material and Methods: An ecological study was conducted using data on pesticide expenditure in 1985 and 1996, and deaths caused by CNS and CVS malformations in infants under 1 year old in 1986-1990 and 1997-2001, respectively. Per capita pesticide consumption and infant mortality rates were calculated for each microregion. Microregions were grouped according to quintiles of pesticide consumption, taking the first quintile as reference. The association between pesticide consumption and infant mortality was examined by calculating Spearman correlation coefficients (r) and mortality rate ratios (RR), stratifying by gender and type of microregion (urban or rural). Results: Significant and positive correlations between per capita pesticide consumption and rates of mortality due to CNS and CVS defects were observed in rural but not urban microregions. In general, mortality RRs for the 2 types of malformations in rural microregions were significantly higher in each quintile of pesticide consumption compared to the lowest quintile in the 2 study periods, with elevations ranging between 10% and 30%. Likewise, mortality RRs in these microregions showed significant trends of increase across quintiles of pesticide consumption in both study periods. In urban areas, however, mortality RRs from both CNS and CVS malformations were weak and not statistically significant, and a trend of increase of mortality with increasing pesticide usage was not observed. Conclusions: The results show the relevance of pesticide exposure in rural areas with intense agricultural activity, suggesting that such prenatal exposures may be related with the occurrence of certain congenital defects.
EN
In everyday life an important component of working efficiency is people’s physical capabilities and normal level of functioning of basic systems of the organism. One of the most popular means of physical culture among growing generation is health-improving fitness and its technologies. Aim of the article: research of influence of the health-improving fitness on level of physical activity and functional state of cardiovascular system of 11th form pupils. Methods of research: theoretical analysis and generalization of scientific and methodological literature and internet sources, pedagogical supervision, sociologic (questioning), pulsometry and Ruffier reaction, methods of mathematical statistics. Results of research. Research has shown that 70 % of pupils have mid-level degree cardiac insufficiency, 20 % got “good” marks and only 10 % of pupils have high indicators that correspond to mark “excellent”. The results of the questioning have shown that level of physical activity of 60 % youngsters is not sufficient in connection with low motivation for physical culture training. Research of pupils of the 11th form showed that among means of health-improving factors, the most popular among girls are classical and fitball-aerobics, yoga and pilates; amongs boys – athletics, gymnastycs, health-improving jogging, crossfit, riding a bicycle and health-improving swimming. Use of the means of health-improving fitness (basic aerobics) at physical training classes considerably influenced the increase of physical activity level, optimization of cardiovascular system of youngsters and increase of motivation to physical training classes. Conclusions. The research proves that at physical training classes the main issue that provokes 11th form pupils to take care about their own health is a possibility to choose among those means of physical education that entail fresh interest to classes. The use of health-improving element helped in optimization of work of cardiovascular system, increased level of physical activity and adolescent’s interest that proves its important place among other types of health-improving technologies. Perspectives of further researches lie within advanced learning of foreign experience of using health-improving fitness technologies.
EN
ObjectivesA method of continuous heart rate (HR) and blood pressure (BP) recording was used for the evaluation of the cardiovascular system parameters in participants of short-term (<1 month) high-latitude expeditions, in comparison with the parameters of residents of Central Russia and the Arctic region.Material and MethodsA dynamic examination of participants of Arctic expeditions (30 men, residents of middle-latitude regions, aged 46.7±1.7 years), workers permanently living in Central Russia (the Moscow region, 44 men, aged 46.7±1.0 years) and residents of the North (the Murmansk region, 35 men, aged 46.6±1.3 years) was performed. The authors used a spiroartheriocardiorythmograph allowing the parallel recording of HR, BP, spectral characteristics of HR variability (HRV) and the variability of systolic BP (sBP) and diastolic BP (dBP), cardiac performance parameters, and spontaneous baroreflex sensitivity (BRS). The parameters were recorded at rest, in a sitting position, over 2 min.ResultsThe basic clinical parameters (HR, BP and cardiac performance) did not differ in the workers living in different climatic zones. However, the residents of the North demonstrated a lower total power (TP) of the dBP variability spectrum and a lower relative power of the high-frequency (HF) range in both the sBP and dBP variability spectra. The participants of expeditions to the North had a lower TP of the HRV spectrum (in comparison with both control groups) that did not change during the expeditions; BRS was reduced, while the TP of the sBP spectrum was increased in comparison with the corresponding parameters obtained from the residents of circumpolar regions, and decreased during the expedition in parallel with a decrease in the sBP values. The TP of both the sBP and dBP variability spectra, as well as the power of the HF range in these spectra, were similar in the participants of expeditions to those obtained from the residents of Central Russia, and they considerably surpassed the corresponding parameters in the northerners surveyed.ConclusionsThe revealed peculiarities of the cardiovascular system in the participants of high-latitude expeditions can be considered as correlates of positive, and adequate in terms of the physiological value, adaptive shifts in the autonomous regulation of the cardiovascular system.
EN
Impedance cardiography seems to be a very good, although underappreciated diagnostic method. What may distinguish it from among the many research methods is the fact that it enables non-invasive monitoring of cardiac output, stroke volume and systemic vascular resistance. Holter recording of the hemodynamic parameters makes it possible to study them not only in stationary (hospital, outpatient clinic) conditions, but also during household or professional activities, e.g., during road vehicle driving. Assessment of the trends of changes in the circulatory system of the employee at work makes it possible to judge whether the type of work performed by the worker is well tolerated – whether it is not too hard or too stressful. This is important, therefore, impedance cardiography can be extensively used in occupational medicine. Provision of preventive care to workers according to current standards requires, on the one hand, the use of the latest diagnostic methods while, on the other hand, the methods must be inexpensive, because otherwise the employer would not be able or willing to pay the associated costs. Impedance cardiography meets those criteria; however, few data is available in literature worldwide on the use of this method in the research on the impact of occupational work on cardiovascular responses of the employees. This work reports the use of impedance cardiography in studies on the various aspects of work environment.
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Grelina – niewielki peptyd, WIELKIE możliwości

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PL
Grelina jest hormonem polipeptydowym, syntezowanym głównie w dnie i trzonie żołądka przez komórki neuroendokrynne X/A. Swoje działanie wywiera za pośrednictwem receptorów GHS-R1a, które zlokalizowane są w większości narządów organizmu. Sekrecja greliny jest wieloczynnikowa, a zależy od szeregu endo- i egzogennych bodźców. Stanowi ona jeden z głównych związków regulujących funkcje metaboliczne ustroju. Grelina silnie wpływa na stymulację apetytu, przez co nazywana jest „hormonem głodu”. Poza tym hormon ten współdziała w regulacji gospodarki węglowodanowo-lipidowej organizmu, zmniejszając sekrecję insuliny w trzustce, oraz nasila proces adipogenezy. Oprócz tego, istotne są własności przeciwzapalne greliny oraz jej wpływ na osteogenezę, układ sercowo-naczyniowy, pokarmowy czy procesy reprodukcyjne. Udowodniono również pozytywny wpływ greliny na procesy pamięci długoterminowej oraz przestrzennej.
EN
Ghrelin is a polypeptide-like hormone, synthesized mainly in stomach fundus and body by the neuroendocrine X/A cells. It works via GHS-R1a receptors, which are localized in numerous organs. Ghrelin secretion is multifactorial and depends on plenty of endo- and egzogenous conditions. As investigated, ghrelin is one of the most significant compounds taking part in human metabolism. It was nicknamed “the hunger hormone” after its role in appetite stimulation. Moreover, ghrelin interacts with carbohydrate and lipid metabolism, decreasing insulin secretion and intensifies adipogenesis process. Other functions of ghrelin are inter alia the anti-inflammatory effect, the role in osteogenesis process, alimentary and reproductive processes and its influence on the cardio-vascular system. It was also found that ghrelin is involved in positive impact on long-term and spatial memory.
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