Komórki macierzyste. Część II – pluripotencjalne komórki macierzyste

• Authors: Barbara Świerczek , Damian Dudka , Karolina Archacka

Title variants

EN

Stem cells. Part II – pluripotent stem cells

• Languages of publication: PL EN

Abstracts

EN

Pluripotent stem cells are able to differentiate into all types of cells and tissues buliding mammalian organism. During embryo development pluripotent cells are localized in the inner cell mass of blastocyst, which serves as a source of cells for embryo body formation. Pluripotent cells building inner cell mass can be isolated and propagated in vitro as embryonic stem cells (ES cells). Another type of pluripotent stem cells, i.e. induced pluripotent stem cells (iPS cells), is derived as a result of the process called cell reprogramming. Both ES cells and iPS cells serve as a valuable research tool. They could also be used as a potential source of cells for transplantation in regenerative medicine. Derivation of both ES and iPS cells is considered as a real breakthrough in science and medicine, and was distinguished by the Nobel Prize in physiology or medicine. In 2007 Mario Capecchi, Olivier Smithies, and Martin Evans were awarded for development of methods which enabled derivation of ES cells and genetic modification of mice, while in 2012 John Gurdon and Shinya Yamanaka were awarded for research focused on cell reprogramming.

Keywords

EN

Pluripotent stem cells; ES cells; iPS cells; reprogramming; multidirectional differentiation; regenerative medicine; cell therapies

• Publisher: Instytut Badań Edukacyjnych
• Journal: Edukacja Biologiczna i Środowiskowa
• Year: 2013
• Issue: 2
• Pages: 3-11

Dates

published

2013-06-28

Contributors

author

Barbara Świerczek

• Uniwersytet Warszawski, Wydział Biologii

author

Damian Dudka

• Uniwersytet Warszawski, Wydział Biologii

author

Karolina Archacka

• Uniwersytet Warszawski, Wydział Biologii